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Complement factor h autoantibodies and age-related macular degeneration.
Dhillon B, Wright AF, Tufail A, Pappworth I, Hayward C, Moore I, Strain L, Kavanagh D, Barlow PN, Herbert AP, Schmidt CQ, Armbrecht AM, Laude A, Deary IJ, Staniforth SJ, Holmes LV, Goodship TH, Marchbank KJ. Dhillon B, et al. Among authors: barlow pn. Invest Ophthalmol Vis Sci. 2010 Nov;51(11):5858-63. doi: 10.1167/iovs.09-5124. Epub 2010 Jun 30. Invest Ophthalmol Vis Sci. 2010. PMID: 20592223
Structure shows that a glycosaminoglycan and protein recognition site in factor H is perturbed by age-related macular degeneration-linked single nucleotide polymorphism.
Herbert AP, Deakin JA, Schmidt CQ, Blaum BS, Egan C, Ferreira VP, Pangburn MK, Lyon M, Uhrín D, Barlow PN. Herbert AP, et al. Among authors: barlow pn. J Biol Chem. 2007 Jun 29;282(26):18960-8. doi: 10.1074/jbc.M609636200. Epub 2007 Mar 13. J Biol Chem. 2007. PMID: 17360715 Free article.
Structural basis for complement factor H linked age-related macular degeneration.
Prosser BE, Johnson S, Roversi P, Herbert AP, Blaum BS, Tyrrell J, Jowitt TA, Clark SJ, Tarelli E, Uhrín D, Barlow PN, Sim RB, Day AJ, Lea SM. Prosser BE, et al. Among authors: barlow pn. J Exp Med. 2007 Oct 1;204(10):2277-83. doi: 10.1084/jem.20071069. Epub 2007 Sep 24. J Exp Med. 2007. PMID: 17893204 Free PMC article.
A new map of glycosaminoglycan and C3b binding sites on factor H.
Schmidt CQ, Herbert AP, Kavanagh D, Gandy C, Fenton CJ, Blaum BS, Lyon M, Uhrín D, Barlow PN. Schmidt CQ, et al. Among authors: barlow pn. J Immunol. 2008 Aug 15;181(4):2610-9. doi: 10.4049/jimmunol.181.4.2610. J Immunol. 2008. PMID: 18684951
134 results