Barreca ML - Search Results

1

Pharmacological inactivation of the prion protein by targeting a folding intermediate.

Spagnolli G, Massignan T, Astolfi A, Biggi S, Rigoli M, Brunelli P, Libergoli M, Ianeselli A, Orioli S, Boldrini A, Terruzzi L, Bonaldo V, Maietta G, Lorenzo NL, Fernandez LC, Codeseira YB, Tosatto L, Linsenmeier L, Vignoli B, Petris G, Gasparotto D, Pennuto M, Guella G, Canossa M, Altmeppen HC, Lolli G, Biressi S, Pastor MM, Requena JR, Mancini I, Barreca ML, Faccioli P, Biasini E. Spagnolli G, et al. Among authors: barreca ml. Commun Biol. 2021 Jan 12;4(1):62. doi: 10.1038/s42003-020-01585-x. Commun Biol. 2021. PMID: 33437023 Free PMC article.

2

Decoding the function of the N-terminal tail of the cellular prion protein to inspire novel therapeutic avenues for neurodegenerative diseases.

Iraci N, Stincardini C, Barreca ML, Biasini E. Iraci N, et al. Among authors: barreca ml. Virus Res. 2015 Sep 2;207:62-8. doi: 10.1016/j.virusres.2014.10.015. Epub 2014 Oct 23. Virus Res. 2015. PMID: 25456402 Review.

3

A Comprehensive Structural Overview of p38α MAPK in Complex with Type I Inhibitors.

Astolfi A, Iraci N, Manfroni G, Barreca ML, Cecchetti V. Astolfi A, et al. Among authors: barreca ml. ChemMedChem. 2015 Jun;10(6):957-69. doi: 10.1002/cmdc.201500030. Epub 2015 Apr 9. ChemMedChem. 2015. PMID: 26012502 Review.

4

p38α MAPK and Type I Inhibitors: Binding Site Analysis and Use of Target Ensembles in Virtual Screening.

Astolfi A, Iraci N, Sabatini S, Barreca ML, Cecchetti V. Astolfi A, et al. Among authors: barreca ml. Molecules. 2015 Aug 31;20(9):15842-61. doi: 10.3390/molecules200915842. Molecules. 2015. PMID: 26334265 Free PMC article.

5

A Small-Molecule Inhibitor of Prion Replication and Mutant Prion Protein Toxicity.

Massignan T, Sangiovanni V, Biggi S, Stincardini C, Elezgarai SR, Maietta G, Andreev IA, Ratmanova NK, Belov DS, Lukyanenko ER, Belov GM, Barreca ML, Altieri A, Kurkin AV, Biasini E. Massignan T, et al. Among authors: barreca ml. ChemMedChem. 2017 Aug 22;12(16):1286-1292. doi: 10.1002/cmdc.201700302. Epub 2017 Aug 1. ChemMedChem. 2017. PMID: 28722340

6

A Comprehensive Structural Overview of p38α Mitogen-Activated Protein Kinase in Complex with ATP-Site and Non-ATP-Site Binders.

Astolfi A, Manfroni G, Cecchetti V, Barreca ML. Astolfi A, et al. Among authors: barreca ml. ChemMedChem. 2018 Jan 8;13(1):7-14. doi: 10.1002/cmdc.201700636. Epub 2017 Dec 18. ChemMedChem. 2018. PMID: 29210532 Review.

7

Pharmacological Agents Targeting the Cellular Prion Protein.

Barreca ML, Iraci N, Biggi S, Cecchetti V, Biasini E. Barreca ML, et al. Pathogens. 2018 Mar 7;7(1):27. doi: 10.3390/pathogens7010027. Pathogens. 2018. PMID: 29518975 Free PMC article. Review.

8

Identification of compounds inhibiting prion replication and toxicity by removing PrP^C from the cell surface.

Biggi S, Pancher M, Stincardini C, Luotti S, Massignan T, Dalle Vedove A, Astolfi A, Gatto P, Lolli G, Barreca ML, Bonetto V, Adami V, Biasini E. Biggi S, et al. Among authors: barreca ml. J Neurochem. 2020 Jan;152(1):136-150. doi: 10.1111/jnc.14805. Epub 2019 Jul 18. J Neurochem. 2020. PMID: 31264722 Free article.

9

Deciphering the Molecular Recognition Mechanism of Multidrug Resistance Staphylococcus aureus NorA Efflux Pump Using a Supervised Molecular Dynamics Approach.

Palazzotti D, Bissaro M, Bolcato G, Astolfi A, Felicetti T, Sabatini S, Sturlese M, Cecchetti V, Barreca ML, Moro S. Palazzotti D, et al. Among authors: barreca ml. Int J Mol Sci. 2019 Aug 19;20(16):4041. doi: 10.3390/ijms20164041. Int J Mol Sci. 2019. PMID: 31430864 Free PMC article.

10

Discovery of potent p38α MAPK inhibitors through a funnel like workflow combining in silico screening and in vitro validation.

Astolfi A, Kudolo M, Brea J, Manni G, Manfroni G, Palazzotti D, Sabatini S, Cecchetti F, Felicetti T, Cannalire R, Massari S, Tabarrini O, Loza MI, Fallarino F, Cecchetti V, Laufer SA, Barreca ML. Astolfi A, et al. Among authors: barreca ml. Eur J Med Chem. 2019 Nov 15;182:111624. doi: 10.1016/j.ejmech.2019.111624. Epub 2019 Aug 16. Eur J Med Chem. 2019. PMID: 31445234

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