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Tau-Centric Multitarget Approach for Alzheimer's Disease: Development of First-in-Class Dual Glycogen Synthase Kinase 3β and Tau-Aggregation Inhibitors.
Gandini A, Bartolini M, Tedesco D, Martinez-Gonzalez L, Roca C, Campillo NE, Zaldivar-Diez J, Perez C, Zuccheri G, Miti A, Feoli A, Castellano S, Petralla S, Monti B, Rossi M, Moda F, Legname G, Martinez A, Bolognesi ML. Gandini A, et al. Among authors: bartolini m. J Med Chem. 2018 Sep 13;61(17):7640-7656. doi: 10.1021/acs.jmedchem.8b00610. Epub 2018 Aug 24. J Med Chem. 2018. PMID: 30078314
Advanced analytical methodologies in Alzheimer's disease drug discovery.
De Simone A, Naldi M, Tedesco D, Bartolini M, Davani L, Andrisano V. De Simone A, et al. Among authors: bartolini m. J Pharm Biomed Anal. 2020 Jan 30;178:112899. doi: 10.1016/j.jpba.2019.112899. Epub 2019 Sep 29. J Pharm Biomed Anal. 2020. PMID: 31606562 Free article. Review.
Discovery of an Allosteric Ligand Binding Site in SMYD3 Lysine Methyltransferase.
Talibov VO, Fabini E, FitzGerald EA, Tedesco D, Cederfeldt D, Talu MJ, Rachman MM, Mihalic F, Manoni E, Naldi M, Sanese P, Forte G, Lepore Signorile M, Barril X, Simone C, Bartolini M, Dobritzsch D, Del Rio A, Danielson UH. Talibov VO, et al. Among authors: bartolini m. Chembiochem. 2021 May 4;22(9):1597-1608. doi: 10.1002/cbic.202000736. Epub 2021 Feb 11. Chembiochem. 2021. PMID: 33400854 Free PMC article.
Application of the SMALP technology to the isolation of GPCRs from low-yielding cell lines.
Tedesco D, Maj M, Malarczyk P, Cingolani A, Zaffagnini M, Wnorowski A, Czapiński J, Benelli T, Mazzoni R, Bartolini M, Jóźwiak K. Tedesco D, et al. Among authors: bartolini m. Biochim Biophys Acta Biomembr. 2021 Sep 1;1863(9):183641. doi: 10.1016/j.bbamem.2021.183641. Epub 2021 May 10. Biochim Biophys Acta Biomembr. 2021. PMID: 33984320 Free article.
375 results