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Basic Red 51, a permitted semi-permanent hair dye, is cytotoxic to human skin cells: Studies in monolayer and 3D skin model using human keratinocytes (HaCaT).
Zanoni TB, Tiago M, Faião-Flores F, de Moraes Barros SB, Bast A, Hageman G, de Oliveira DP, Maria-Engler SS. Zanoni TB, et al. Toxicol Lett. 2014 Jun 5;227(2):139-49. doi: 10.1016/j.toxlet.2014.03.007. Epub 2014 Mar 20. Toxicol Lett. 2014. PMID: 24657526
The carcinogenic potential of hair dye ingredients has attracted the attention of toxicologists for many decades, mainly due to the fact that some ingredients belong to the large chemical family of aromatic amines. Herein, we investigated the cytotoxicity of Basic Red …
The carcinogenic potential of hair dye ingredients has attracted the attention of toxicologists for many decades, mainly due to the fact tha …
Hues of risk: investigating genotoxicity and environmental impacts of azo textile dyes.
Ramamurthy K, Priya PS, Murugan R, Arockiaraj J. Ramamurthy K, et al. Environ Sci Pollut Res Int. 2024 Apr 27. doi: 10.1007/s11356-024-33444-1. Online ahead of print. Environ Sci Pollut Res Int. 2024. PMID: 38676865 Review.
Examining different families of textile dye which contain azo group in their structure such as Sudan I and Sudan III Sudan IV, Basic Red 51, Basic Violet 14, Disperse Yellow 7, Congo Red, Acid Red 26, and Acid Blue 113 reveals their carcinogenic potential, wh …
Examining different families of textile dye which contain azo group in their structure such as Sudan I and Sudan III Sudan IV, Basic …
Immortalized equivalent human epidermis as a platform to evaluation hair dyes toxicity: Efficiency comparison between 3D and monolayer culture.
Mini CA, Dorta DJ, Maria-Engler SS, Oliveira DP. Mini CA, et al. Chem Biol Interact. 2020 Oct 1;330:109227. doi: 10.1016/j.cbi.2020.109227. Epub 2020 Aug 18. Chem Biol Interact. 2020. PMID: 32818478 Free article.
In this work, we used a three-dimensional in-house model of epidermis using HaCaT immortalized cells to evaluate the dermal toxicity induced by Basic Blue 99 and Basic Red 51, both present in commercial hair dye formulations. Our data show that cells cultured …
In this work, we used a three-dimensional in-house model of epidermis using HaCaT immortalized cells to evaluate the dermal toxicity induced …
Cytotoxic and genotoxic effects of two hair dyes used in the formulation of black color.
Tafurt-Cardona Y, Suares-Rocha P, Fernandes TC, Marin-Morales MA. Tafurt-Cardona Y, et al. Food Chem Toxicol. 2015 Dec;86:9-15. doi: 10.1016/j.fct.2015.09.010. Epub 2015 Sep 21. Food Chem Toxicol. 2015. PMID: 26404083
In this study, we investigated the toxic effects of two hair dyes, Basic Red 51 (BR51) and Basic Brown 17 (BB17), which are temporary dyes of the azo group (R-N=N-R'), used in the composition of the black hair dye. ...
In this study, we investigated the toxic effects of two hair dyes, Basic Red 51 (BR51) and Basic Brown 17 (BB17), which …
Functional cardiotoxicity assessment of cosmetic compounds using human-induced pluripotent stem cell-derived cardiomyocytes.
Chaudhari U, Nemade H, Sureshkumar P, Vinken M, Ates G, Rogiers V, Hescheler J, Hengstler JG, Sachinidis A. Chaudhari U, et al. Arch Toxicol. 2018 Jan;92(1):371-381. doi: 10.1007/s00204-017-2065-z. Epub 2017 Sep 22. Arch Toxicol. 2018. PMID: 28940058 Free PMC article.
Here, five cosmetic ingredients were studied by the new hiPSC-CMs test; kojic acid (KJA), triclosan (TS), triclocarban (TCC), 2,7-naphthalenediol (NPT), and basic red 51 (BR51) based on cytotoxicity as well as ATP assays, beating rate, and genomic biomarkers …
Here, five cosmetic ingredients were studied by the new hiPSC-CMs test; kojic acid (KJA), triclosan (TS), triclocarban (TCC), 2,7-naphthalen …
Toxicity of dyes to zebrafish at the biochemical level: Cellular energy allocation and neurotoxicity.
Abe FR, Soares AMVM, Oliveira DP, Gravato C. Abe FR, et al. Environ Pollut. 2018 Apr;235:255-262. doi: 10.1016/j.envpol.2017.12.020. Epub 2018 Jan 4. Environ Pollut. 2018. PMID: 29291525
Thus, the current study was designed to assess the effects induced by the synthetic azo dye Basic Red 51 (BR51) and by the natural naphthoquinone dye erythrostominone (ERY) on zebrafish early life stages (Danio rerio) at different biological organization leve …
Thus, the current study was designed to assess the effects induced by the synthetic azo dye Basic Red 51 (BR51) and by …
Toxicological and behavioral responses as a tool to assess the effects of natural and synthetic dyes on zebrafish early life.
Abe FR, Mendonça JN, Moraes LA, Oliveira GA, Gravato C, Soares AM, Oliveira DP. Abe FR, et al. Chemosphere. 2017 Jul;178:282-290. doi: 10.1016/j.chemosphere.2017.03.030. Epub 2017 Mar 9. Chemosphere. 2017. PMID: 28340455
Thereby, toxicity tests to non-target organisms are critical step to develop harmless dyes to environment and in this context, zebrafish early life stages are becoming an important alternative model. We aimed to assess the toxic effects of the synthetic dye Basic Red …
Thereby, toxicity tests to non-target organisms are critical step to develop harmless dyes to environment and in this context, zebrafish ear …
Aryldiazonium Salts as Nitrogen-Based Lewis Acids: Facile Synthesis of Tuneable Azophosphonium Salts.
Habraken ERM, van Leest NP, Hooijschuur P, de Bruin B, Ehlers AW, Lutz M, Slootweg JC. Habraken ERM, et al. Angew Chem Int Ed Engl. 2018 Sep 10;57(37):11929-11933. doi: 10.1002/anie.201806913. Epub 2018 Aug 20. Angew Chem Int Ed Engl. 2018. PMID: 30051582
Inspired by the commercially available azoimidazolium dyes (e.g., Basic Red 51) that can be obtained from aryldiazonium salts and N-heterocyclic carbenes, we developed the synthesis of a unique set of arylazophosphonium salts. ...
Inspired by the commercially available azoimidazolium dyes (e.g., Basic Red 51) that can be obtained from aryldiazonium …
Life history and behavior effects of synthetic and natural dyes on Daphnia magna.
Abe FR, Machado AL, Soares AMVM, Oliveira DP, Pestana JLT. Abe FR, et al. Chemosphere. 2019 Dec;236:124390. doi: 10.1016/j.chemosphere.2019.124390. Epub 2019 Jul 17. Chemosphere. 2019. PMID: 31344623 Free article.
Here, we aimed to evaluate toxic effects induced by the synthetic azo dye Basic Red 51 (BR51) in comparison with natural dye erythrostominone (Ery) in the microcrustacean Daphnia magna, a standard organism used to assess the risk of chemicals to aquatic organ …
Here, we aimed to evaluate toxic effects induced by the synthetic azo dye Basic Red 51 (BR51) in comparison with natura …
Biochemical approaches to assess oxidative stress induced by exposure to natural and synthetic dyes in early life stages in zebrafish.
Abe FR, Gravato C, Soares AMVM, de Oliveira DP. Abe FR, et al. J Toxicol Environ Health A. 2017;80(23-24):1259-1268. doi: 10.1080/15287394.2017.1371091. Epub 2017 Sep 11. J Toxicol Environ Health A. 2017. PMID: 28891787
The aim of this study was to utilize a multibiomarker approach to examine underlying oxidative stress mechanisms triggered by sublethal concentrations of synthetic azo dye Basic Red 51 (BR51), the natural dye erythrostominone (ERY), and its light-degraded pro …
The aim of this study was to utilize a multibiomarker approach to examine underlying oxidative stress mechanisms triggered by sublethal conc …
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