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CARD8 inflammasome activation triggers pyroptosis in human T cells.
Linder A, Bauernfried S, Cheng Y, Albanese M, Jung C, Keppler OT, Hornung V. Linder A, et al. Among authors: bauernfried s. EMBO J. 2020 Oct 1;39(19):e105071. doi: 10.15252/embj.2020105071. Epub 2020 Aug 25. EMBO J. 2020. PMID: 32840892 Free PMC article.
Human NLRP1: From the shadows to center stage.
Bauernfried S, Hornung V. Bauernfried S, et al. J Exp Med. 2022 Jan 3;219(1):e20211405. doi: 10.1084/jem.20211405. Epub 2021 Dec 15. J Exp Med. 2022. PMID: 34910085 Free PMC article. Review.
ZAKα-driven ribotoxic stress response activates the human NLRP1 inflammasome.
Robinson KS, Toh GA, Rozario P, Chua R, Bauernfried S, Sun Z, Firdaus MJ, Bayat S, Nadkarni R, Poh ZS, Tham KC, Harapas CR, Lim CK, Chu W, Tay CWS, Tan KY, Zhao T, Bonnard C, Sobota R, Connolly JE, Common J, Masters SL, Chen KW, Ho L, Wu B, Hornung V, Zhong FL. Robinson KS, et al. Among authors: bauernfried s. Science. 2022 Jul 15;377(6603):328-335. doi: 10.1126/science.abl6324. Epub 2022 Jul 14. Science. 2022. PMID: 35857590 Free PMC article.
DPP9 restrains NLRP1 activation.
Bauernfried S, Hornung V. Bauernfried S, et al. Nat Struct Mol Biol. 2021 Apr;28(4):333-336. doi: 10.1038/s41594-021-00580-y. Nat Struct Mol Biol. 2021. PMID: 33785922 No abstract available.
Human NLRP1 is a sensor for double-stranded RNA.
Bauernfried S, Scherr MJ, Pichlmair A, Duderstadt KE, Hornung V. Bauernfried S, et al. Science. 2021 Jan 29;371(6528):eabd0811. doi: 10.1126/science.abd0811. Epub 2020 Nov 26. Science. 2021. PMID: 33243852
[No title available]
[No authors listed] [No authors listed] PMID: 33453817
C-tag TNF: a reporter system to study TNF shedding.
Pinci F, Gaidt MM, Jung C, Kuut G, Jackson MA, Bauernfried S, Hornung V. Pinci F, et al. Among authors: bauernfried s. J Biol Chem. 2020 Dec 25;295(52):18065-18075. doi: 10.1074/jbc.RA120.015248. Epub 2020 Oct 20. J Biol Chem. 2020. PMID: 33082141 Free PMC article.
Three exposures to the spike protein of SARS-CoV-2 by either infection or vaccination elicit superior neutralizing immunity to all variants of concern.
Wratil PR, Stern M, Priller A, Willmann A, Almanzar G, Vogel E, Feuerherd M, Cheng CC, Yazici S, Christa C, Jeske S, Lupoli G, Vogt T, Albanese M, Mejías-Pérez E, Bauernfried S, Graf N, Mijocevic H, Vu M, Tinnefeld K, Wettengel J, Hoffmann D, Muenchhoff M, Daechert C, Mairhofer H, Krebs S, Fingerle V, Graf A, Steininger P, Blum H, Hornung V, Liebl B, Überla K, Prelog M, Knolle P, Keppler OT, Protzer U. Wratil PR, et al. Among authors: bauernfried s. Nat Med. 2022 Mar;28(3):496-503. doi: 10.1038/s41591-022-01715-4. Epub 2022 Jan 28. Nat Med. 2022. PMID: 35090165
Novel Poxin Stable cGAMP-Derivatives Are Remarkable STING Agonists.
Stazzoni S, Böhmer DFR, Hernichel F, Özdemir D, Pappa A, Drexler D, Bauernfried S, Witte G, Wagner M, Veth S, Hopfner KP, Hornung V, König LM, Carell T. Stazzoni S, et al. Among authors: bauernfried s. Angew Chem Int Ed Engl. 2022 Oct 4;61(40):e202207175. doi: 10.1002/anie.202207175. Epub 2022 Aug 31. Angew Chem Int Ed Engl. 2022. PMID: 35876840 Free PMC article.
12 results