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Changes in apoptotic mechanisms following penetrating ballistic-like brain injury.
Cartagena CM, Schmid KE, Phillips KL, Tortella FC, Dave JR. Cartagena CM, et al. J Mol Neurosci. 2013 Feb;49(2):301-11. doi: 10.1007/s12031-012-9828-z. Epub 2012 Jun 11. J Mol Neurosci. 2013. PMID: 22684621
For the mitochondria-mediated apoptosis pathway, RQs of anti-apoptotic factors bcl2a1d and birc3 were upregulated while both bcl2 and bax were downregulated. ...
For the mitochondria-mediated apoptosis pathway, RQs of anti-apoptotic factors bcl2a1d and birc3 were upregulated while both bcl2 and …
Progesterone inhibits apoptosis in part by PGRMC1-regulated gene expression.
Peluso JJ, Liu X, Gawkowska A, Lodde V, Wu CA. Peluso JJ, et al. Mol Cell Endocrinol. 2010 May 14;320(1-2):153-61. doi: 10.1016/j.mce.2010.02.005. Epub 2010 Feb 6. Mol Cell Endocrinol. 2010. PMID: 20144686 Free PMC article.
P4's anti-apoptotic action is also attenuated by actinomycin D, an inhibitor of RNA synthesis, and P4 activation of PGRMC1 suppresses Bad and increases Bcl2a1d expression. Taken together, the present studies suggest a genomic component to PGRMC1's anti-apoptotic mechanism …
P4's anti-apoptotic action is also attenuated by actinomycin D, an inhibitor of RNA synthesis, and P4 activation of PGRMC1 suppresses Bad an …
Gene expression profiling of common signal transduction pathways affected by rBMSCs/F92A-Cav1 in the lungs of rat with pulmonary arterial hypertension.
Chen H, Yang H, Xu C, Yue H, Xia P, Strappe PM, Wang L, Pan L, Tang W, Chen S, Wang L. Chen H, et al. Biomed Pharmacother. 2016 Oct;83:100-106. doi: 10.1016/j.biopha.2016.06.028. Epub 2016 Jun 23. Biomed Pharmacother. 2016. PMID: 27470556
RESULTS: Screening with the Rat Signal Transduction PathwayFinder R(2) PCR Array system and subsequent western blot, immunohistochemistry or real time PCR analysis revealed that F92A-Cav1 modified rBMSCs can inhibit the inflammation factors (TNF-alpha, Icam1 and C/EBPdelta), pro- …
RESULTS: Screening with the Rat Signal Transduction PathwayFinder R(2) PCR Array system and subsequent western blot, immunohistochemistry or …