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Finding new drugs to enhance anion secretion in cystic fibrosis: Toward suitable systems for better drug screening. Report on the pre-conference meeting to the 12th ECFS Basic Science Conference, Albufeira, 25-28 March 2015.
Verkman AS, Edelman A, Amaral M, Mall MA, Beekman JM, Meiners T, Galietta LJ, Bear CE. Verkman AS, et al. Among authors: bear ce. J Cyst Fibros. 2015 Nov;14(6):700-5. doi: 10.1016/j.jcf.2015.10.001. Epub 2015 Oct 21. J Cyst Fibros. 2015. PMID: 26474804 Free PMC article. No abstract available.
ATPase assay of purified, reconstituted CFTR protein.
Kogan I, Ramjeesingh M, Bear CE. Kogan I, et al. Among authors: bear ce. J Cyst Fibros. 2004 Aug;3 Suppl 2:133-4. doi: 10.1016/j.jcf.2004.05.028. J Cyst Fibros. 2004. PMID: 15463945 Free article.
Lung arginase expression and activity is increased in cystic fibrosis mouse models.
Jaecklin T, Duerr J, Huang H, Rafii M, Bear CE, Ratjen F, Pencharz P, Kavanagh BP, Mall MA, Grasemann H. Jaecklin T, et al. Among authors: bear ce. J Appl Physiol (1985). 2014 Aug 1;117(3):284-8. doi: 10.1152/japplphysiol.00167.2014. Epub 2014 Jun 12. J Appl Physiol (1985). 2014. PMID: 24925982 Free article.
The CF Canada-Sick Kids Program in individual CF therapy: A resource for the advancement of personalized medicine in CF.
Eckford PDW, McCormack J, Munsie L, He G, Stanojevic S, Pereira SL, Ho K, Avolio J, Bartlett C, Yang JY, Wong AP, Wellhauser L, Huan LJ, Jiang JX, Ouyang H, Du K, Klingel M, Kyriakopoulou L, Gonska T, Moraes TJ, Strug LJ, Rossant J, Ratjen F, Bear CE. Eckford PDW, et al. Among authors: bear ce. J Cyst Fibros. 2019 Jan;18(1):35-43. doi: 10.1016/j.jcf.2018.03.013. Epub 2018 Oct 10. J Cyst Fibros. 2019. PMID: 29685812 Free article. Review.
Functional rescue of c.3846G>A (W1282X) in patient-derived nasal cultures achieved by inhibition of nonsense mediated decay and protein modulators with complementary mechanisms of action.
Laselva O, Eckford PD, Bartlett C, Ouyang H, Gunawardena TN, Gonska T, Moraes TJ, Bear CE. Laselva O, et al. Among authors: bear ce. J Cyst Fibros. 2020 Sep;19(5):717-727. doi: 10.1016/j.jcf.2019.12.001. Epub 2019 Dec 9. J Cyst Fibros. 2020. PMID: 31831337 Free article.
Riociguat for the treatment of Phe508del homozygous adults with cystic fibrosis.
Derichs N, Taylor-Cousar JL, Davies JC, Fajac I, Tullis E, Nazareth D, Downey DG, Rosenbluth D, Malfroot A, Saunders C, Jensen R, Solomon GM, Vermeulen F, Kaiser A, Willmann S, Saleh S, Droebner K, Sandner P, Bear CE, Hoffmann A, Ratjen F, Rowe SM; Rio-CF Study Group. Derichs N, et al. Among authors: bear ce. J Cyst Fibros. 2021 Nov;20(6):1018-1025. doi: 10.1016/j.jcf.2021.07.015. Epub 2021 Aug 19. J Cyst Fibros. 2021. PMID: 34419414 Free article. Clinical Trial.
Antisense oligonucleotide splicing modulation as a novel Cystic Fibrosis therapeutic approach for the W1282X nonsense mutation.
Oren YS, Avizur-Barchad O, Ozeri-Galai E, Elgrabli R, Schirelman MR, Blinder T, Stampfer CD, Ordan M, Laselva O, Cohen-Cymberknoh M, Kerem E, Bear CE, Kerem B. Oren YS, et al. Among authors: bear ce. J Cyst Fibros. 2022 Jul;21(4):630-636. doi: 10.1016/j.jcf.2021.12.012. Epub 2021 Dec 28. J Cyst Fibros. 2022. PMID: 34972649 Free article.
CFTR interactome mapping using the mammalian membrane two-hybrid high-throughput screening system.
Lim SH, Snider J, Birimberg-Schwartz L, Ip W, Serralha JC, Botelho HM, Lopes-Pacheco M, Pinto MC, Moutaoufik MT, Zilocchi M, Laselva O, Esmaeili M, Kotlyar M, Lyakisheva A, Tang P, López Vázquez L, Akula I, Aboualizadeh F, Wong V, Grozavu I, Opacak-Bernardi T, Yao Z, Mendoza M, Babu M, Jurisica I, Gonska T, Bear CE, Amaral MD, Stagljar I. Lim SH, et al. Among authors: bear ce. Mol Syst Biol. 2022 Feb;18(2):e10629. doi: 10.15252/msb.202110629. Mol Syst Biol. 2022. PMID: 35156780 Free PMC article.
172 results