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Diversity-oriented synthesis-facilitated medicinal chemistry: toward the development of novel antimalarial agents.
J Med Chem. 2014 Oct 23;57(20):8496-502. doi: 10.1021/jm500994n. Epub 2014 Oct 13.
J Med Chem. 2014.
PMID: 25211597
Free PMC article.
Diversity-oriented synthesis probe targets Plasmodium falciparum cytochrome b ubiquinone reduction site and synergizes with oxidation site inhibitors.
Lukens AK, Heidebrecht RW Jr, Mulrooney C, Beaudoin JA, Comer E, Duvall JR, Fitzgerald ME, Masi D, Galinsky K, Scherer CA, Palmer M, Munoz B, Foley M, Schreiber SL, Wiegand RC, Wirth DF.
Lukens AK, et al. Among authors: beaudoin ja.
J Infect Dis. 2015 Apr 1;211(7):1097-103. doi: 10.1093/infdis/jiu565. Epub 2014 Oct 21.
J Infect Dis. 2015.
PMID: 25336726
Free PMC article.
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Diversity-Oriented Synthesis Yields a Novel Lead for the Treatment of Malaria.
Heidebrecht RW Jr, Mulrooney C, Austin CP, Barker RH Jr, Beaudoin JA, Cheng KC, Comer E, Dandapani S, Dick J, Duvall JR, Ekland EH, Fidock DA, Fitzgerald ME, Foley M, Guha R, Hinkson P, Kramer M, Lukens AK, Masi D, Marcaurelle LA, Su XZ, Thomas CJ, Weïwer M, Wiegand RC, Wirth D, Xia M, Yuan J, Zhao J, Palmer M, Munoz B, Schreiber S.
Heidebrecht RW Jr, et al. Among authors: beaudoin ja.
ACS Med Chem Lett. 2012 Feb 9;3(2):112-117. doi: 10.1021/ml200244k. Epub 2011 Dec 22.
ACS Med Chem Lett. 2012.
PMID: 22328964
Free PMC article.
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Synthesis of a D-Ala-D-Ala peptide isostere via olefin cross-metathesis and evaluation of vancomycin binding.
Quinn RK, Cianci AL, Beaudoin JA, Sculimbrene BR.
Quinn RK, et al. Among authors: beaudoin ja.
Bioorg Med Chem Lett. 2010 Aug 1;20(15):4382-5. doi: 10.1016/j.bmcl.2010.06.065. Epub 2010 Jun 15.
Bioorg Med Chem Lett. 2010.
PMID: 20594838
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