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Structural basis for inhibition of protein-tyrosine phosphatase 1B by isothiazolidinone heterocyclic phosphonate mimetics.
J Biol Chem. 2006 Oct 27;281(43):32784-95. doi: 10.1074/jbc.M606873200. Epub 2006 Aug 17.
J Biol Chem. 2006.
PMID: 16916797
Free article.
Structure-based design and discovery of protein tyrosine phosphatase inhibitors incorporating novel isothiazolidinone heterocyclic phosphotyrosine mimetics.
Combs AP, Yue EW, Bower M, Ala PJ, Wayland B, Douty B, Takvorian A, Polam P, Wasserman Z, Zhu W, Crawley ML, Pruitt J, Sparks R, Glass B, Modi D, McLaughlin E, Bostrom L, Li M, Galya L, Blom K, Hillman M, Gonneville L, Reid BG, Wei M, Becker-Pasha M, Klabe R, Huber R, Li Y, Hollis G, Burn TC, Wynn R, Liu P, Metcalf B.
Combs AP, et al. Among authors: becker pasha m.
J Med Chem. 2005 Oct 20;48(21):6544-8. doi: 10.1021/jm0504555.
J Med Chem. 2005.
PMID: 16220970
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Structural insights into the design of nonpeptidic isothiazolidinone-containing inhibitors of protein-tyrosine phosphatase 1B.
Ala PJ, Gonneville L, Hillman M, Becker-Pasha M, Yue EW, Douty B, Wayland B, Polam P, Crawley ML, McLaughlin E, Sparks RB, Glass B, Takvorian A, Combs AP, Burn TC, Hollis GF, Wynn R.
Ala PJ, et al. Among authors: becker pasha m.
J Biol Chem. 2006 Dec 8;281(49):38013-21. doi: 10.1074/jbc.M607913200. Epub 2006 Oct 6.
J Biol Chem. 2006.
PMID: 17028182
Free article.
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Combined inhibition of Janus kinase 1/2 for the treatment of JAK2V617F-driven neoplasms: selective effects on mutant cells and improvements in measures of disease severity.
Liu PC, Caulder E, Li J, Waeltz P, Margulis A, Wynn R, Becker-Pasha M, Li Y, Crowgey E, Hollis G, Haley P, Sparks RB, Combs AP, Rodgers JD, Burn TC, Vaddi K, Fridman JS.
Liu PC, et al. Among authors: becker pasha m.
Clin Cancer Res. 2009 Nov 15;15(22):6891-900. doi: 10.1158/1078-0432.CCR-09-1298. Epub 2009 Nov 3.
Clin Cancer Res. 2009.
PMID: 19887489
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Phosphorylation State-Dependent High Throughput Screening of the c-Met Kinase.
Behshad E, Klabe RM, Margulis A, Becker-Pasha M, Rupar MJ, Collier P, Liu PC, Hollis GF, Burn TC, Wynn R.
Behshad E, et al. Among authors: becker pasha m.
Curr Chem Genomics. 2010 Apr 23;4:27-33. doi: 10.2174/1875397301004010027.
Curr Chem Genomics. 2010.
PMID: 20556206
Free PMC article.
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High-throughput determination of mode of inhibition in lead identification and optimization.
Wei M, Wynn R, Hollis G, Liao B, Margulis A, Reid BG, Klabe R, Liu PC, Becker-Pasha M, Rupar M, Burn TC, McCall DE, Li Y.
Wei M, et al. Among authors: becker pasha m.
J Biomol Screen. 2007 Mar;12(2):220-8. doi: 10.1177/1087057106296679.
J Biomol Screen. 2007.
PMID: 17351185
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