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Sirtuins in yeast: phenotypes and tools.
Tsuchiyama S, Kwan E, Dang W, Bedalov A, Kennedy BK. Tsuchiyama S, et al. Among authors: bedalov a. Methods Mol Biol. 2013;1077:11-37. doi: 10.1007/978-1-62703-637-5_2. Methods Mol Biol. 2013. PMID: 24014397
Substrate-specific activation of sirtuins by resveratrol.
Kaeberlein M, McDonagh T, Heltweg B, Hixon J, Westman EA, Caldwell SD, Napper A, Curtis R, DiStefano PS, Fields S, Bedalov A, Kennedy BK. Kaeberlein M, et al. Among authors: bedalov a. J Biol Chem. 2005 Apr 29;280(17):17038-45. doi: 10.1074/jbc.M500655200. Epub 2005 Jan 31. J Biol Chem. 2005. PMID: 15684413 Free article.
Biology, Chemistry, and Pharmacology of Sirtuins.
Bedalov A, Chowdhury S, Simon JA. Bedalov A, et al. Methods Enzymol. 2016;574:183-211. doi: 10.1016/bs.mie.2016.03.011. Epub 2016 Mar 28. Methods Enzymol. 2016. PMID: 27423863
Identification of selective inhibitors of NAD+-dependent deacetylases using phenotypic screens in yeast.
Hirao M, Posakony J, Nelson M, Hruby H, Jung M, Simon JA, Bedalov A. Hirao M, et al. Among authors: bedalov a. J Biol Chem. 2003 Dec 26;278(52):52773-82. doi: 10.1074/jbc.M308966200. Epub 2003 Oct 8. J Biol Chem. 2003. PMID: 14534292 Free article.
The two enzymes are highly homologous yet have different sensitivity to the small-molecule inhibitor splitomicin (compound 1) (Bedalov, A., Gatbonton, T., Irvine, W. P., Gottschling, D. E., and Simon, J. A. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 15 …
The two enzymes are highly homologous yet have different sensitivity to the small-molecule inhibitor splitomicin (compound 1) (Bedalov
Genetic basis of proteome variation in yeast.
Foss EJ, Radulovic D, Shaffer SA, Ruderfer DM, Bedalov A, Goodlett DR, Kruglyak L. Foss EJ, et al. Among authors: bedalov a. Nat Genet. 2007 Nov;39(11):1369-75. doi: 10.1038/ng.2007.22. Epub 2007 Oct 21. Nat Genet. 2007. PMID: 17952072
71 results