Benkovic SJ - Search Results

1

The purinosome, a multi-protein complex involved in the de novo biosynthesis of purines in humans.

Zhao H, French JB, Fang Y, Benkovic SJ. Zhao H, et al. Among authors: benkovic sj. Chem Commun (Camb). 2013 May 18;49(40):4444-52. doi: 10.1039/c3cc41437j. Epub 2013 Apr 11. Chem Commun (Camb). 2013. PMID: 23575936 Free PMC article.

2

Direct demonstration of the active salvage of preformed purines by murine tumors.

Johnson DL, Mullin RJ, Duch DS, Benkovic SJ. Johnson DL, et al. Among authors: benkovic sj. Biochem Biophys Res Commun. 1990 Aug 16;170(3):1164-9. doi: 10.1016/0006-291x(90)90515-o. Biochem Biophys Res Commun. 1990. PMID: 2390083

3

Reversible compartmentalization of de novo purine biosynthetic complexes in living cells.

An S, Kumar R, Sheets ED, Benkovic SJ. An S, et al. Among authors: benkovic sj. Science. 2008 Apr 4;320(5872):103-6. doi: 10.1126/science.1152241. Science. 2008. PMID: 18388293

4

Dynamic regulation of a metabolic multi-enzyme complex by protein kinase CK2.

An S, Kyoung M, Allen JJ, Shokat KM, Benkovic SJ. An S, et al. Among authors: benkovic sj. J Biol Chem. 2010 Apr 9;285(15):11093-9. doi: 10.1074/jbc.M110.101139. Epub 2010 Feb 15. J Biol Chem. 2010. PMID: 20157113 Free PMC article.

5

Microtubule-assisted mechanism for functional metabolic macromolecular complex formation.

An S, Deng Y, Tomsho JW, Kyoung M, Benkovic SJ. An S, et al. Among authors: benkovic sj. Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):12872-6. doi: 10.1073/pnas.1008451107. Epub 2010 Jul 6. Proc Natl Acad Sci U S A. 2010. PMID: 20615962 Free PMC article.

6

GPCRs regulate the assembly of a multienzyme complex for purine biosynthesis.

Verrier F, An S, Ferrie AM, Sun H, Kyoung M, Deng H, Fang Y, Benkovic SJ. Verrier F, et al. Among authors: benkovic sj. Nat Chem Biol. 2011 Oct 23;7(12):909-15. doi: 10.1038/nchembio.690. Nat Chem Biol. 2011. PMID: 22020552 Free PMC article.

7

Mapping protein-protein proximity in the purinosome.

Deng Y, Gam J, French JB, Zhao H, An S, Benkovic SJ. Deng Y, et al. Among authors: benkovic sj. J Biol Chem. 2012 Oct 19;287(43):36201-7. doi: 10.1074/jbc.M112.407056. Epub 2012 Sep 6. J Biol Chem. 2012. PMID: 22955281 Free PMC article.

8

Hsp70/Hsp90 chaperone machinery is involved in the assembly of the purinosome.

French JB, Zhao H, An S, Niessen S, Deng Y, Cravatt BF, Benkovic SJ. French JB, et al. Among authors: benkovic sj. Proc Natl Acad Sci U S A. 2013 Feb 12;110(7):2528-33. doi: 10.1073/pnas.1300173110. Epub 2013 Jan 28. Proc Natl Acad Sci U S A. 2013. PMID: 23359685 Free PMC article.

9

Lab-on-a-chip technologies for single-molecule studies.

Zhao Y, Chen D, Yue H, French JB, Rufo J, Benkovic SJ, Huang TJ. Zhao Y, et al. Among authors: benkovic sj. Lab Chip. 2013 Jun 21;13(12):2183-98. doi: 10.1039/c3lc90042h. Epub 2013 May 14. Lab Chip. 2013. PMID: 23670195 Free PMC article.

10

Functional significance of evolving protein sequence in dihydrofolate reductase from bacteria to humans.

Liu CT, Hanoian P, French JB, Pringle TH, Hammes-Schiffer S, Benkovic SJ. Liu CT, et al. Among authors: benkovic sj. Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):10159-64. doi: 10.1073/pnas.1307130110. Epub 2013 Jun 3. Proc Natl Acad Sci U S A. 2013. PMID: 23733948 Free PMC article.

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