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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1982 1
1986 1
1989 1
1990 1
1992 2
1993 2
1995 1
1996 2
2000 2
2001 5
2002 1
2003 3
2005 4
2006 8
2007 6
2008 4
2009 13
2010 14
2011 14
2012 19
2013 13
2014 39
2015 47
2016 58
2017 66
2018 79
2019 95
2020 141
2021 158
2022 144
2023 154
2024 77

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1,013 results

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Page 1
Berberine and health outcomes: An umbrella review.
Li Z, Wang Y, Xu Q, Ma J, Li X, Yan J, Tian Y, Wen Y, Chen T. Li Z, et al. Phytother Res. 2023 May;37(5):2051-2066. doi: 10.1002/ptr.7806. Epub 2023 Mar 31. Phytother Res. 2023. PMID: 36999891 Review.
Berberine is a plant extract widely used in clinical practice. This review aimed to summarize and to grade the available evidence on the association between berberine consumption and health-related outcomes. ...Additionally, the clinical effects of berberi …
Berberine is a plant extract widely used in clinical practice. This review aimed to summarize and to grade the available evidence on …
Berberine and Its Role in Chronic Disease.
Cicero AF, Baggioni A. Cicero AF, et al. Adv Exp Med Biol. 2016;928:27-45. doi: 10.1007/978-3-319-41334-1_2. Adv Exp Med Biol. 2016. PMID: 27671811 Review.
Berberine is a quaternary ammonium salt from the protoberberine group of isoquinoline alkaloids. ...Moreover, preliminary clinical evidence suggest the ability of berberine to reduce endothelial inflammation improving vascular health, even in patients already …
Berberine is a quaternary ammonium salt from the protoberberine group of isoquinoline alkaloids. ...Moreover, preliminary clinical ev …
Berberine in Cardiovascular and Metabolic Diseases: From Mechanisms to Therapeutics.
Feng X, Sureda A, Jafari S, Memariani Z, Tewari D, Annunziata G, Barrea L, Hassan STS, Šmejkal K, Malaník M, Sychrová A, Barreca D, Ziberna L, Mahomoodally MF, Zengin G, Xu S, Nabavi SM, Shen AZ. Feng X, et al. Theranostics. 2019 Mar 16;9(7):1923-1951. doi: 10.7150/thno.30787. eCollection 2019. Theranostics. 2019. PMID: 31037148 Free PMC article. Review.
Cardiovascular and metabolic diseases (CVMD) are the leading causes of death worldwide, underscoring the urgent necessity to develop new pharmacotherapies. Berberine (BBR) is an eminent component of traditional Chinese and Ayurvedic medicine for more than 2000 years. ...
Cardiovascular and metabolic diseases (CVMD) are the leading causes of death worldwide, underscoring the urgent necessity to develop new pha …
Berberine: Pharmacological Features in Health, Disease and Aging.
Gasmi A, Asghar F, Zafar S, Oliinyk P, Khavrona O, Lysiuk R, Peana M, Piscopo S, Antonyak H, Pen JJ, Lozynska I, Noor S, Lenchyk L, Muhammad A, Vladimirova I, Dub N, Antoniv O, Tsal O, Upyr T, Bjørklund G. Gasmi A, et al. Curr Med Chem. 2024;31(10):1214-1234. doi: 10.2174/0929867330666230207112539. Curr Med Chem. 2024. PMID: 36748808 Review.
METHODS: Representative studies were considered and analyzed from different scientific databases, including PubMed and Web of Science, for the years 1982-2022. RESULTS: Literature analysis shows that berberine affects many biochemical and pharmacological pathways that theo …
METHODS: Representative studies were considered and analyzed from different scientific databases, including PubMed and Web of Science, for t …
Comparative efficacy of oral insulin sensitizers metformin, thiazolidinediones, inositol, and berberine in improving endocrine and metabolic profiles in women with PCOS: a network meta-analysis.
Zhao H, Xing C, Zhang J, He B. Zhao H, et al. Reprod Health. 2021 Aug 18;18(1):171. doi: 10.1186/s12978-021-01207-7. Reprod Health. 2021. PMID: 34407851 Free PMC article.
BACKGROUND: Multiple oral insulin-sensitizing agents, such as metformin, thiazolidinediones, inositols, and berberine, have been proven safe and efficacious in improving the endocrine, metabolic, and reproductive abnormalities seen in polycystic ovary syndrome (PCOS), prov …
BACKGROUND: Multiple oral insulin-sensitizing agents, such as metformin, thiazolidinediones, inositols, and berberine, have been prov …
Anticancer Effects and Mechanisms of Berberine from Medicinal Herbs: An Update Review.
Xiong RG, Huang SY, Wu SX, Zhou DD, Yang ZJ, Saimaiti A, Zhao CN, Shang A, Zhang YJ, Gan RY, Li HB. Xiong RG, et al. Molecules. 2022 Jul 15;27(14):4523. doi: 10.3390/molecules27144523. Molecules. 2022. PMID: 35889396 Free PMC article. Review.
Cancer has been a serious public health problem. Berberine is a famous natural compound from medicinal herbs and shows many bioactivities, such as antioxidant, anti-inflammatory, antidiabetic, anti-obesity, and antimicrobial activities. ...In addition, the nanotechn …
Cancer has been a serious public health problem. Berberine is a famous natural compound from medicinal herbs and shows many bi …
Effects of Berberine against Pancreatitis and Pancreatic Cancer.
Vlavcheski F, O'Neill EJ, Gagacev F, Tsiani E. Vlavcheski F, et al. Molecules. 2022 Dec 6;27(23):8630. doi: 10.3390/molecules27238630. Molecules. 2022. PMID: 36500723 Free PMC article. Review.
Inflammation and fibrosis caused by chronic pancreatitis exacerbate malignant transformation and significantly increase the risk of developing pancreatic cancer, the world's most aggressive cancer with a 5-year survival rate less than 10%. Berberine (BBR) is a naturally oc …
Inflammation and fibrosis caused by chronic pancreatitis exacerbate malignant transformation and significantly increase the risk of developi …
Combined berberine and probiotic treatment as an effective regimen for improving postprandial hyperlipidemia in type 2 diabetes patients: a double blinded placebo controlled randomized study.
Wang S, Ren H, Zhong H, Zhao X, Li C, Ma J, Gu X, Xue Y, Huang S, Yang J, Chen L, Chen G, Qu S, Liang J, Qin L, Huang Q, Peng Y, Li Q, Wang X, Zou Y, Shi Z, Li X, Li T, Yang H, Lai S, Xu G, Li J, Zhang Y, Gu Y, Wang W. Wang S, et al. Gut Microbes. 2022 Jan-Dec;14(1):2003176. doi: 10.1080/19490976.2021.2003176. Gut Microbes. 2022. PMID: 34923903 Free PMC article. Clinical Trial.
In this study, we aimed to evaluate whether the therapy combining probiotics (Prob) and berberine (BBR), a proven antidiabetic and hypolipidemic regimen via altering gut microbiome, could effectively reduce PL in T2D and to explore the underlying mechanism. ...
In this study, we aimed to evaluate whether the therapy combining probiotics (Prob) and berberine (BBR), a proven antidiabetic and hy …
Berberine ameliorates depression-like behaviors in mice via inhibiting NLRP3 inflammasome-mediated neuroinflammation and preventing neuroplasticity disruption.
Qin Z, Shi DD, Li W, Cheng D, Zhang YD, Zhang S, Tsoi B, Zhao J, Wang Z, Zhang ZJ. Qin Z, et al. J Neuroinflammation. 2023 Mar 1;20(1):54. doi: 10.1186/s12974-023-02744-7. J Neuroinflammation. 2023. PMID: 36859349 Free PMC article.
RNA-sequencing identified that NLRP3 was markedly upregulated after long-term CORT exposure. Berberine reversed the concentrations of peripheral and brain cytokines, NLRP3 inflammasome elicited by CORT in the prefrontal cortex and hippocampus were decreased by berberine …
RNA-sequencing identified that NLRP3 was markedly upregulated after long-term CORT exposure. Berberine reversed the concentrations of …
Therapeutic effect of berberine on metabolic diseases: Both pharmacological data and clinical evidence.
Xu X, Yi H, Wu J, Kuang T, Zhang J, Li Q, Du H, Xu T, Jiang G, Fan G. Xu X, et al. Biomed Pharmacother. 2021 Jan;133:110984. doi: 10.1016/j.biopha.2020.110984. Epub 2020 Nov 10. Biomed Pharmacother. 2021. PMID: 33186794 Free article. Review.
The increased incidence of metabolic diseases (e.g., diabetes and obesity) has seriously affected human health and life safety worldwide. It is of great significance to find effective drugs from natural compounds to treat metabolic diseases. Berberine (BBR), an impo …
The increased incidence of metabolic diseases (e.g., diabetes and obesity) has seriously affected human health and life safety worldw …
1,013 results