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Targeting the epigenome for treatment of cancer.
Geutjes EJ, Bajpe PK, Bernards R. Geutjes EJ, et al. Among authors: bernards r. Oncogene. 2012 Aug 23;31(34):3827-44. doi: 10.1038/onc.2011.552. Epub 2011 Dec 5. Oncogene. 2012. PMID: 22139071
p27kip1-independent cell cycle regulation by MYC.
Berns K, Martins C, Dannenberg JH, Berns A, te Riele H, Bernards R. Berns K, et al. Among authors: bernards r. Oncogene. 2000 Oct 5;19(42):4822-7. doi: 10.1038/sj.onc.1203879. Oncogene. 2000. PMID: 11039898
New tools for functional mammalian cancer genetics.
Brummelkamp TR, Bernards R. Brummelkamp TR, et al. Among authors: bernards r. Nat Rev Cancer. 2003 Oct;3(10):781-9. doi: 10.1038/nrc1191. Nat Rev Cancer. 2003. PMID: 14570045 Review.
A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer.
Berns K, Horlings HM, Hennessy BT, Madiredjo M, Hijmans EM, Beelen K, Linn SC, Gonzalez-Angulo AM, Stemke-Hale K, Hauptmann M, Beijersbergen RL, Mills GB, van de Vijver MJ, Bernards R. Berns K, et al. Among authors: bernards r. Cancer Cell. 2007 Oct;12(4):395-402. doi: 10.1016/j.ccr.2007.08.030. Cancer Cell. 2007. PMID: 17936563 Free article. Clinical Trial.
329 results