Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

46 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Nonpeptidic inhibitors of human leukocyte elastase. 3. Design, synthesis, X-ray crystallographic analysis, and structure-activity relationships for a series of orally active 3-amino-6-phenylpyridin-2-one trifluoromethyl ketones.
Bernstein PR, Andisik D, Bradley PK, Bryant CB, Ceccarelli C, Damewood JR Jr, Earley R, Edwards PD, Feeney S, Gomes BC, et al. Bernstein PR, et al. J Med Chem. 1994 Sep 30;37(20):3313-26. doi: 10.1021/jm00046a016. J Med Chem. 1994. PMID: 7932559
Inhibitors of human leukocyte elastase.
Bernstein PR, Edwards PD, Williams JC. Bernstein PR, et al. Prog Med Chem. 1994;31:59-120. doi: 10.1016/s0079-6468(08)70019-5. Prog Med Chem. 1994. PMID: 8029481 Review. No abstract available.
Design of orally active, non-peptidic inhibitors of human leukocyte elastase.
Brown FJ, Andisik DW, Bernstein PR, Bryant CB, Ceccarelli C, Damewood JR Jr, Edwards PD, Earley RA, Feeney S, Green RC, et al. Brown FJ, et al. Among authors: bernstein pr. J Med Chem. 1994 Apr 29;37(9):1259-61. doi: 10.1021/jm00035a004. J Med Chem. 1994. PMID: 8176703 No abstract available.
Synthetic inhibitors of elastase.
Edwards PD, Bernstein PR. Edwards PD, et al. Among authors: bernstein pr. Med Res Rev. 1994 Mar;14(2):127-94. doi: 10.1002/med.2610140202. Med Res Rev. 1994. PMID: 8189835 Review.
Orally active trifluoromethyl ketone inhibitors of human leukocyte elastase.
Veale CA, Bernstein PR, Bohnert CM, Brown FJ, Bryant C, Damewood JR Jr, Earley R, Feeney SW, Edwards PD, Gomes B, Hulsizer JM, Kosmider BJ, Krell RD, Moore G, Salcedo TW, Shaw A, Silberstein DS, Steelman GB, Stein M, Strimpler A, Thomas RM, Vacek EP, Williams JC, Wolanin DJ, Woolson S. Veale CA, et al. Among authors: bernstein pr. J Med Chem. 1997 Sep 26;40(20):3173-81. doi: 10.1021/jm970250z. J Med Chem. 1997. PMID: 9379436
Design, synthesis, and SAR of tachykinin antagonists: modulation of balance in NK(1)/NK(2) receptor antagonist activity.
Albert JS, Aharony D, Andisik D, Barthlow H, Bernstein PR, Bialecki RA, Dedinas R, Dembofsky BT, Hill D, Kirkland K, Koether GM, Kosmider BJ, Ohnmacht C, Palmer W, Potts W, Rumsey W, Shen L, Shenvi A, Sherwood S, Warwick PJ, Russell K. Albert JS, et al. Among authors: bernstein pr. J Med Chem. 2002 Aug 29;45(18):3972-83. doi: 10.1021/jm020094i. J Med Chem. 2002. PMID: 12190319
De novo design of a picomolar nonbasic 5-HT(1B) receptor antagonist.
Nugiel DA, Krumrine JR, Hill DC, Damewood JR Jr, Bernstein PR, Sobotka-Briner CD, Liu J, Zacco A, Pierson ME. Nugiel DA, et al. Among authors: bernstein pr. J Med Chem. 2010 Feb 25;53(4):1876-80. doi: 10.1021/jm901200t. J Med Chem. 2010. PMID: 20088516
Discovery of novel, orally active dual NK1/NK2 antagonists.
Bernstein PR, Aharony D, Albert JS, Andisik D, Barthlow HG, Bialecki R, Davenport T, Dedinas RF, Dembofsky BT, Koether G, Kosmider BJ, Kirkland K, Ohnmacht CJ, Potts W, Rumsey WL, Shen L, Shenvi A, Sherwood S, Stollman D, Russell K. Bernstein PR, et al. Bioorg Med Chem Lett. 2001 Oct 22;11(20):2769-73. doi: 10.1016/s0960-894x(01)00572-8. Bioorg Med Chem Lett. 2001. PMID: 11591520
46 results