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Nuclear death receptor TRAIL-R2 inhibits maturation of let-7 and promotes proliferation of pancreatic and other tumor cells.
Haselmann V, Kurz A, Bertsch U, Hübner S, Olempska-Müller M, Fritsch J, Häsler R, Pickl A, Fritsche H, Annewanter F, Engler C, Fleig B, Bernt A, Röder C, Schmidt H, Gelhaus C, Hauser C, Egberts JH, Heneweer C, Rohde AM, Böger C, Knippschild U, Röcken C, Adam D, Walczak H, Schütze S, Janssen O, Wulczyn FG, Wajant H, Kalthoff H, Trauzold A. Haselmann V, et al. Among authors: bernt a. Gastroenterology. 2014 Jan;146(1):278-90. doi: 10.1053/j.gastro.2013.10.009. Epub 2013 Oct 9. Gastroenterology. 2014. PMID: 24120475
Myozap Deficiency Promotes Adverse Cardiac Remodeling via Differential Regulation of Mitogen-activated Protein Kinase/Serum-response Factor and β-Catenin/GSK-3β Protein Signaling.
Rangrez AY, Eden M, Poyanmehr R, Kuhn C, Stiebeling K, Dierck F, Bernt A, Lüllmann-Rauch R, Weiler H, Kirchof P, Frank D, Frey N. Rangrez AY, et al. Among authors: bernt a. J Biol Chem. 2016 Feb 19;291(8):4128-43. doi: 10.1074/jbc.M115.689620. Epub 2015 Dec 30. J Biol Chem. 2016. PMID: 26719331 Free PMC article.
The E3 ubiquitin ligase HectD3 attenuates cardiac hypertrophy and inflammation in mice.
Rangrez AY, Borlepawar A, Schmiedel N, Deshpande A, Remes A, Kumari M, Bernt A, Christen L, Helbig A, Jungmann A, Sossalla S, Tholey A, Müller OJ, Frank D, Frey N. Rangrez AY, et al. Among authors: bernt a. Commun Biol. 2020 Oct 9;3(1):562. doi: 10.1038/s42003-020-01289-2. Commun Biol. 2020. PMID: 33037313 Free PMC article.
Myoscape controls cardiac calcium cycling and contractility via regulation of L-type calcium channel surface expression.
Eden M, Meder B, Völkers M, Poomvanicha M, Domes K, Branchereau M, Marck P, Will R, Bernt A, Rangrez A, Busch M; German Mouse Clinic Consortium; Hrabě de Angelis M, Heymes C, Rottbauer W, Most P, Hofmann F, Frey N. Eden M, et al. Among authors: bernt a. Nat Commun. 2016 Apr 28;7:11317. doi: 10.1315/11317. Nat Commun. 2016. PMID: 27122098 Free PMC article.
Cardiac α-Actin (ACTC1) Gene Mutation Causes Atrial-Septal Defects Associated With Late-Onset Dilated Cardiomyopathy.
Frank D, Yusuf Rangrez A, Friedrich C, Dittmann S, Stallmeyer B, Yadav P, Bernt A, Schulze-Bahr E, Borlepawar A, Zimmermann WH, Peischard S, Seebohm G, Linke WA, Baba HA, Krüger M, Unger A, Usinger P, Frey N, Schulze-Bahr E. Frank D, et al. Among authors: bernt a. Circ Genom Precis Med. 2019 Aug;12(8):e002491. doi: 10.1161/CIRCGEN.119.002491. Epub 2019 Aug 20. Circ Genom Precis Med. 2019. PMID: 31430208 Free article.
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