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The androgen receptor in LNCaP cells contains a mutation in the ligand binding domain which affects steroid binding characteristics and response to antiandrogens.
Veldscholte J, Berrevoets CA, Ris-Stalpers C, Kuiper GG, Jenster G, Trapman J, Brinkmann AO, Mulder E. Veldscholte J, et al. Among authors: berrevoets ca. J Steroid Biochem Mol Biol. 1992 Mar;41(3-8):665-9. doi: 10.1016/0960-0760(92)90401-4. J Steroid Biochem Mol Biol. 1992. PMID: 1562539 Review.
Studies on the human prostatic cancer cell line LNCaP.
Veldscholte J, Berrevoets CA, Mulder E. Veldscholte J, et al. Among authors: berrevoets ca. J Steroid Biochem Mol Biol. 1994 Jun;49(4-6):341-6. doi: 10.1016/0960-0760(94)90277-1. J Steroid Biochem Mol Biol. 1994. PMID: 8043498 Review.
Epitope prediction and confirmation for the human androgen receptor: generation of monoclonal antibodies for multi-assay performance following the synthetic peptide strategy.
Zegers ND, Claassen E, Neelen C, Mulder E, van Laar JH, Voorhorst MM, Berrevoets CA, Brinkmann AO, van der Kwast TH, Ruizeveld de Winter JA, et al. Zegers ND, et al. Among authors: berrevoets ca. Biochim Biophys Acta. 1991 Jan 23;1073(1):23-32. doi: 10.1016/0304-4165(91)90178-j. Biochim Biophys Acta. 1991. PMID: 1703791
35 results