Beutner G - Search Results

1

Adventures in Atropisomerism: Total Synthesis of a Complex Active Pharmaceutical Ingredient with Two Chirality Axes.

Beutner G, Carrasquillo R, Geng P, Hsiao Y, Huang EC, Janey J, Katipally K, Kolotuchin S, La Porte T, Lee A, Lobben P, Lora-Gonzalez F, Mack B, Mudryk B, Qiu Y, Qian X, Ramirez A, Razler TM, Rosner T, Shi Z, Simmons E, Stevens J, Wang J, Wei C, Wisniewski SR, Zhu Y. Beutner G, et al. Org Lett. 2018 Jul 6;20(13):3736-3740. doi: 10.1021/acs.orglett.8b01218. Epub 2018 Jun 17. Org Lett. 2018. PMID: 29909639

2

Development of a Diastereoselective Phosphorylation of a Complex Nucleoside via Dynamic Kinetic Resolution.

Tran K, Beutner GL, Schmidt M, Janey J, Chen K, Rosso V, Eastgate MD. Tran K, et al. J Org Chem. 2015 May 15;80(10):4994-5003. doi: 10.1021/acs.joc.5b00392. Epub 2015 Apr 30. J Org Chem. 2015. PMID: 25840459

3

Scalable Synthesis of the Potent HIV Inhibitor BMS-986001 by Non-Enzymatic Dynamic Kinetic Asymmetric Transformation (DYKAT).

Ortiz A, Benkovics T, Beutner GL, Shi Z, Bultman M, Nye J, Sfouggatakis C, Kronenthal DR. Ortiz A, et al. Angew Chem Int Ed Engl. 2015 Jun 8;54(24):7185-8. doi: 10.1002/anie.201502290. Epub 2015 Apr 29. Angew Chem Int Ed Engl. 2015. PMID: 25925234

4

Nickel-Catalyzed Synthesis of Quinazolinediones.

Beutner GL, Hsiao Y, Razler T, Simmons EM, Wertjes W. Beutner GL, et al. Org Lett. 2017 Mar 3;19(5):1052-1055. doi: 10.1021/acs.orglett.7b00052. Epub 2017 Feb 13. Org Lett. 2017. PMID: 28253632

5

Zinc Acetate-Promoted Buchwald-Hartwig Couplings of Heteroaromatic Amines.

Ayothiraman R, Rangaswamy S, Maity P, Simmons EM, Beutner GL, Janey J, Treitler DS, Eastgate MD, Vaidyanathan R. Ayothiraman R, et al. J Org Chem. 2017 Jul 21;82(14):7420-7427. doi: 10.1021/acs.joc.7b01101. Epub 2017 Jul 5. J Org Chem. 2017. PMID: 28677970

6

TCFH-NMI: Direct Access to N-Acyl Imidazoliums for Challenging Amide Bond Formations.

Beutner GL, Young IS, Davies ML, Hickey MR, Park H, Stevens JM, Ye Q. Beutner GL, et al. Org Lett. 2018 Jul 20;20(14):4218-4222. doi: 10.1021/acs.orglett.8b01591. Epub 2018 Jun 29. Org Lett. 2018. PMID: 29956545

7

C-H Arylation in the Formation of a Complex Pyrrolopyridine, the Commercial Synthesis of the Potent JAK2 Inhibitor, BMS-911543.

Fox RJ, Cuniere NL, Bakrania L, Wei C, Strotman NA, Hay M, Fanfair D, Regens C, Beutner GL, Lawler M, Lobben P, Soumeillant MC, Cohen B, Zhu K, Skliar D, Rosner T, Markwalter CE, Hsiao Y, Tran K, Eastgate MD. Fox RJ, et al. J Org Chem. 2019 Apr 19;84(8):4661-4669. doi: 10.1021/acs.joc.8b02383. Epub 2018 Nov 12. J Org Chem. 2019. PMID: 30388009

8

Direct Lewis Acid Catalyzed Conversion of Enantioenriched N-Acyloxazolidinones to Chiral Esters, Amides, and Acids.

Stevens JM, Parra-Rivera AC, Dixon DD, Beutner GL, DelMonte AJ, Frantz DE, Janey JM, Paulson J, Talley MR. Stevens JM, et al. J Org Chem. 2018 Dec 7;83(23):14245-14261. doi: 10.1021/acs.joc.8b02451. Epub 2018 Nov 19. J Org Chem. 2018. PMID: 30412670

9

A Process Chemistry Benchmark for sp²-sp³ Cross Couplings.

Beutner GL, Simmons EM, Ayers S, Bemis CY, Goldfogel MJ, Joe CL, Marshall J, Wisniewski SR. Beutner GL, et al. J Org Chem. 2021 Aug 6;86(15):10380-10396. doi: 10.1021/acs.joc.1c01073. Epub 2021 Jul 13. J Org Chem. 2021. PMID: 34255510

10

Beyond Amide Bond Formation: TCFH as a Reagent for Esterification.

Luis NR, Chung KK, Hickey MR, Lin Z, Beutner GL, Vosburg DA. Luis NR, et al. Among authors: beutner gl. Org Lett. 2024 Apr 12;26(14):2745-2750. doi: 10.1021/acs.orglett.3c01611. Epub 2023 Jun 26. Org Lett. 2024. PMID: 37364890

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