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The kinase inhibitors R406 and GS-9973 impair T cell functions and macrophage-mediated anti-tumor activity of rituximab in chronic lymphocytic leukemia patients.
Colado A, Almejún MB, Podaza E, Risnik D, Stanganelli C, Elías EE, Dos Santos P, Slavutsky I, Fernández Grecco H, Cabrejo M, Bezares RF, Giordano M, Gamberale R, Borge M. Colado A, et al. Among authors: bezares rf. Cancer Immunol Immunother. 2017 Apr;66(4):461-473. doi: 10.1007/s00262-016-1946-y. Epub 2016 Dec 23. Cancer Immunol Immunother. 2017. PMID: 28011996 Free PMC article.
CCR4 expression in a case of cutaneous Richter's transformation of chronic lymphocytic leukemia (CLL) to diffuse large B-cell lymphoma (DLBCL) and in CLL patients with no skin manifestations.
Nannini PR, Borge M, Mikolaitis VC, Abreu C, Morande PE, Zanetti SR, Oppezzo P, Palacios F, Ledesma I, Bezares RF, Giordano M, Gamberale R. Nannini PR, et al. Among authors: bezares rf. Eur J Haematol. 2011 Jul;87(1):80-6. doi: 10.1111/j.1600-0609.2011.01613.x. Eur J Haematol. 2011. PMID: 21443542
The cytotoxic activity of Aplidin in chronic lymphocytic leukemia (CLL) is mediated by a direct effect on leukemic cells and an indirect effect on monocyte-derived cells.
Morande PE, Zanetti SR, Borge M, Nannini P, Jancic C, Bezares RF, Bitsmans A, González M, Rodríguez AL, Galmarini CM, Gamberale R, Giordano M. Morande PE, et al. Among authors: bezares rf. Invest New Drugs. 2012 Oct;30(5):1830-40. doi: 10.1007/s10637-011-9740-3. Epub 2011 Sep 2. Invest New Drugs. 2012. PMID: 21887502
54 results