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A minimal threshold of FANCJ helicase activity is required for its response to replication stress or double-strand break repair.
Bharti SK, Sommers JA, Awate S, Bellani MA, Khan I, Bradley L, King GA, Seol Y, Vidhyasagar V, Wu Y, Abe T, Kobayashi K, Shin-Ya K, Kitao H, Wold MS, Branzei D, Neuman KC, Brosh RM Jr. Bharti SK, et al. Nucleic Acids Res. 2018 Jul 6;46(12):6238-6256. doi: 10.1093/nar/gky403. Nucleic Acids Res. 2018. PMID: 29788478 Free PMC article.
Biochemical Characterization of the Human Mitochondrial Replicative Twinkle Helicase: SUBSTRATE SPECIFICITY, DNA BRANCH MIGRATION, AND ABILITY TO OVERCOME BLOCKADES TO DNA UNWINDING.
Khan I, Crouch JD, Bharti SK, Sommers JA, Carney SM, Yakubovskaya E, Garcia-Diaz M, Trakselis MA, Brosh RM Jr. Khan I, et al. Among authors: bharti sk. J Biol Chem. 2016 Jul 1;291(27):14324-14339. doi: 10.1074/jbc.M115.712026. Epub 2016 May 11. J Biol Chem. 2016. PMID: 27226550 Free PMC article.
78 results