Decorin-mediated inhibition of colorectal cancer growth and migration is associated with E-cadherin in vitro and in mice.
Bi X, Pohl NM, Qian Z, Yang GR, Gou Y, Guzman G, Kajdacsy-Balla A, Iozzo RV, Yang W.
Bi X, et al.
Carcinogenesis. 2012 Feb;33(2):326-30. doi: 10.1093/carcin/bgr293. Epub 2011 Dec 8.
Carcinogenesis. 2012.
PMID: 22159220
Free PMC article.
Previous studies have shown that decorin expression is significantly reduced in colorectal cancer tissues and cancer cells, and genetic deletion of the decorin gene is sufficient to cause intestinal tumor formation in mice, resulting from a downregulation of p21, p27(kip1) and E- …
Previous studies have shown that decorin expression is significantly reduced in colorectal cancer tissues and cancer cells, and genetic dele …