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Page 1
Microglial activation in the right amygdala-entorhinal-hippocampal complex is associated with preserved spatial learning in AppNL-G-F mice.
Biechele G, Wind K, Blume T, Sacher C, Beyer L, Eckenweber F, Franzmeier N, Ewers M, Zott B, Lindner S, Gildehaus FJ, von Ungern-Sternberg B, Tahirovic S, Willem M, Bartenstein P, Cumming P, Rominger A, Herms J, Brendel M. Biechele G, et al. Neuroimage. 2021 Apr 15;230:117707. doi: 10.1016/j.neuroimage.2020.117707. Epub 2020 Dec 29. Neuroimage. 2021. PMID: 33385560 Free article.
Asymmetry of Fibrillar Plaque Burden in Amyloid Mouse Models.
Sacher C, Blume T, Beyer L, Biechele G, Sauerbeck J, Eckenweber F, Deussing M, Focke C, Parhizkar S, Lindner S, Gildehaus FJ, von Ungern-Sternberg B, Baumann K, Tahirovic S, Kleinberger G, Willem M, Haass C, Bartenstein P, Cumming P, Rominger A, Herms J, Brendel M. Sacher C, et al. Among authors: biechele g. J Nucl Med. 2020 Dec;61(12):1825-1831. doi: 10.2967/jnumed.120.242750. Epub 2020 May 15. J Nucl Med. 2020. PMID: 32414948 Free article.
Longitudinal TSPO expression in tau transgenic P301S mice predicts increased tau accumulation and deteriorated spatial learning.
Eckenweber F, Medina-Luque J, Blume T, Sacher C, Biechele G, Wind K, Deussing M, Briel N, Lindner S, Boening G, von Ungern-Sternberg B, Unterrainer M, Albert NL, Zwergal A, Levin J, Bartenstein P, Cumming P, Rominger A, Höglinger GU, Herms J, Brendel M. Eckenweber F, et al. Among authors: biechele g. J Neuroinflammation. 2020 Jul 13;17(1):208. doi: 10.1186/s12974-020-01883-5. J Neuroinflammation. 2020. PMID: 32660586 Free PMC article.
Higher CSF sTREM2 and microglia activation are associated with slower rates of beta-amyloid accumulation.
Ewers M, Biechele G, Suárez-Calvet M, Sacher C, Blume T, Morenas-Rodriguez E, Deming Y, Piccio L, Cruchaga C, Kleinberger G, Shaw L, Trojanowski JQ, Herms J, Dichgans M; Alzheimer's Disease Neuroimaging Initiative (ADNI); Brendel M, Haass C, Franzmeier N. Ewers M, et al. Among authors: biechele g. EMBO Mol Med. 2020 Sep 7;12(9):e12308. doi: 10.15252/emmm.202012308. Epub 2020 Aug 10. EMBO Mol Med. 2020. PMID: 32790063 Free PMC article.
In Vivo Assessment of Neuroinflammation in 4-Repeat Tauopathies.
Palleis C, Sauerbeck J, Beyer L, Harris S, Schmitt J, Morenas-Rodriguez E, Finze A, Nitschmann A, Ruch-Rubinstein F, Eckenweber F, Biechele G, Blume T, Shi Y, Weidinger E, Prix C, Bötzel K, Danek A, Rauchmann BS, Stöcklein S, Lindner S, Unterrainer M, Albert NL, Wetzel C, Rupprecht R, Rominger A, Bartenstein P, Herms J, Perneczky R, Haass C, Levin J, Höglinger GU, Brendel M. Palleis C, et al. Among authors: biechele g. Mov Disord. 2021 Apr;36(4):883-894. doi: 10.1002/mds.28395. Epub 2020 Nov 27. Mov Disord. 2021. PMID: 33245166 Free article.
Glial activation is moderated by sex in response to amyloidosis but not to tau pathology in mouse models of neurodegenerative diseases.
Biechele G, Franzmeier N, Blume T, Ewers M, Luque JM, Eckenweber F, Sacher C, Beyer L, Ruch-Rubinstein F, Lindner S, Gildehaus FJ, von Ungern-Sternberg B, Cumming P, Bartenstein P, Rominger A, Höglinger GU, Herms J, Brendel M. Biechele G, et al. J Neuroinflammation. 2020 Dec 14;17(1):374. doi: 10.1186/s12974-020-02046-2. J Neuroinflammation. 2020. PMID: 33317543 Free PMC article.
Cortical [18 F]PI-2620 Binding Differentiates Corticobasal Syndrome Subtypes.
Palleis C, Brendel M, Finze A, Weidinger E, Bötzel K, Danek A, Beyer L, Nitschmann A, Kern M, Biechele G, Rauchmann BS, Häckert J, Höllerhage M, Stephens AW, Drzezga A, van Eimeren T, Villemagne VL, Schildan A, Barthel H, Patt M, Sabri O; German Imaging Initiative for Tauopathies (GII4T); Bartenstein P, Perneczky R, Haass C, Levin J, Höglinger GU. Palleis C, et al. Among authors: biechele g. Mov Disord. 2021 Sep;36(9):2104-2115. doi: 10.1002/mds.28624. Epub 2021 May 5. Mov Disord. 2021. PMID: 33951244
Glitter in the Darkness? Nonfibrillar β-Amyloid Plaque Components Significantly Impact the β-Amyloid PET Signal in Mouse Models of Alzheimer Disease.
Biechele G, Monasor LS, Wind K, Blume T, Parhizkar S, Arzberger T, Sacher C, Beyer L, Eckenweber F, Gildehaus FJ, von Ungern-Sternberg B, Willem M, Bartenstein P, Cumming P, Rominger A, Herms J, Lichtenthaler SF, Haass C, Tahirovic S, Brendel M. Biechele G, et al. J Nucl Med. 2022 Jan;63(1):117-124. doi: 10.2967/jnumed.120.261858. Epub 2021 May 20. J Nucl Med. 2022. PMID: 34016733 Free PMC article.
Feasibility of short imaging protocols for [18F]PI-2620 tau-PET in progressive supranuclear palsy.
Song M, Scheifele M, Barthel H, van Eimeren T, Beyer L, Marek K, Eckenweber F, Palleis C, Kaiser L, Finze A, Kern M, Nitschmann A, Biechele G, Katzdobler S, Bischof G, Hammes J, Jessen F, Saur D, Schroeter ML, Rumpf JJ, Rullmann M, Schildan A, Patt M, Neumaier B, Stephens AW, Rauchmann BS, Perneczky R, Levin J, Classen J, Höglinger GU, Bartenstein P, Boening G, Ziegler S, Villemagne V, Drzezga A, Seibyl J, Sabri O, Brendel M; German Imaging Initiative for Tauopathies (GII4T). Song M, et al. Among authors: biechele g. Eur J Nucl Med Mol Imaging. 2021 Nov;48(12):3872-3885. doi: 10.1007/s00259-021-05391-3. Epub 2021 May 22. Eur J Nucl Med Mol Imaging. 2021. PMID: 34021393 Free PMC article.
Binding characteristics of [18F]PI-2620 distinguish the clinically predicted tau isoform in different tauopathies by PET.
Song M, Beyer L, Kaiser L, Barthel H, van Eimeren T, Marek K, Nitschmann A, Scheifele M, Palleis C, Respondek G, Kern M, Biechele G, Hammes J, Bischof G, Barbe M, Onur Ö, Jessen F, Saur D, Schroeter ML, Rumpf JJ, Rullmann M, Schildan A, Patt M, Neumaier B, Barret O, Madonia J, Russell DS, Stephens AW, Mueller A, Roeber S, Herms J, Bötzel K, Danek A, Levin J, Classen J, Höglinger GU, Bartenstein P, Villemagne V, Drzezga A, Seibyl J, Sabri O, Boening G, Ziegler S, Brendel M. Song M, et al. Among authors: biechele g. J Cereb Blood Flow Metab. 2021 Nov;41(11):2957-2972. doi: 10.1177/0271678X211018904. Epub 2021 May 27. J Cereb Blood Flow Metab. 2021. PMID: 34044665 Free PMC article.
28 results