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Striatal infusion of cholesterol promotes dose-dependent behavioral benefits and exerts disease-modifying effects in Huntington's disease mice.
Birolini G, Valenza M, Di Paolo E, Vezzoli E, Talpo F, Maniezzi C, Caccia C, Leoni V, Taroni F, Bocchi VD, Conforti P, Sogne E, Petricca L, Cariulo C, Verani M, Caricasole A, Falqui A, Biella G, Cattaneo E. Birolini G, et al. Among authors: biella g. EMBO Mol Med. 2020 Oct 7;12(10):e12519. doi: 10.15252/emmm.202012519. Epub 2020 Sep 22. EMBO Mol Med. 2020. PMID: 32959531 Free PMC article.
Inhibiting pathologically active ADAM10 rescues synaptic and cognitive decline in Huntington's disease.
Vezzoli E, Caron I, Talpo F, Besusso D, Conforti P, Battaglia E, Sogne E, Falqui A, Petricca L, Verani M, Martufi P, Caricasole A, Bresciani A, Cecchetti O, Rivetti di Val Cervo P, Sancini G, Riess O, Nguyen H, Seipold L, Saftig P, Biella G, Cattaneo E, Zuccato C. Vezzoli E, et al. Among authors: biella g. J Clin Invest. 2019 May 6;129(6):2390-2403. doi: 10.1172/JCI120616. eCollection 2019 May 6. J Clin Invest. 2019. PMID: 31063986 Free PMC article.
Molecular and functional definition of the developing human striatum.
Onorati M, Castiglioni V, Biasci D, Cesana E, Menon R, Vuono R, Talpo F, Laguna Goya R, Lyons PA, Bulfamante GP, Muzio L, Martino G, Toselli M, Farina C, Barker RA, Biella G, Cattaneo E. Onorati M, et al. Among authors: biella g. Nat Neurosci. 2014 Dec;17(12):1804-15. doi: 10.1038/nn.3860. Epub 2014 Nov 10. Nat Neurosci. 2014. PMID: 25383901
Stem Cell-Derived Human Striatal Progenitors Innervate Striatal Targets and Alleviate Sensorimotor Deficit in a Rat Model of Huntington Disease.
Besusso D, Schellino R, Boido M, Belloli S, Parolisi R, Conforti P, Faedo A, Cernigoj M, Campus I, Laporta A, Bocchi VD, Murtaj V, Parmar M, Spaiardi P, Talpo F, Maniezzi C, Toselli MG, Biella G, Moresco RM, Vercelli A, Buffo A, Cattaneo E. Besusso D, et al. Among authors: biella g. Stem Cell Reports. 2020 May 12;14(5):876-891. doi: 10.1016/j.stemcr.2020.03.018. Epub 2020 Apr 16. Stem Cell Reports. 2020. PMID: 32302555 Free PMC article.
151 results