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IGF-binding proteins secreted by cancer-associated fibroblasts induce context-dependent drug sensitization of lung cancer cells.
Remsing Rix LL, Sumi NJ, Hu Q, Desai B, Bryant AT, Li X, Welsh EA, Fang B, Kinose F, Kuenzi BM, Chen YA, Antonia SJ, Lovly CM, Koomen JM, Haura EB, Marusyk A, Rix U. Remsing Rix LL, et al. Among authors: desai b. Sci Signal. 2022 Aug 16;15(747):eabj5879. doi: 10.1126/scisignal.abj5879. Epub 2022 Aug 16. Sci Signal. 2022. PMID: 35973030 Free PMC article.
Addressing the human cost in a changing climate.
Desai B, Bresch DN, Cazabat C, Hochrainer-Stigler S, Mechler R, Ponserre S, Schewe J. Desai B, et al. Science. 2021 Jun 18;372(6548):1284-1287. doi: 10.1126/science.abh4283. Science. 2021. PMID: 34140380 No abstract available.
A Small-Molecule Pan-Id Antagonist Inhibits Pathologic Ocular Neovascularization.
Wojnarowicz PM, Lima E Silva R, Ohnaka M, Lee SB, Chin Y, Kulukian A, Chang SH, Desai B, Garcia Escolano M, Shah R, Garcia-Cao M, Xu S, Kadam R, Goldgur Y, Miller MA, Ouerfelli O, Yang G, Arakawa T, Albanese SK, Garland WA, Stoller G, Chaudhary J, Norton L, Soni RK, Philip J, Hendrickson RC, Iavarone A, Dannenberg AJ, Chodera JD, Pavletich N, Lasorella A, Campochiaro PA, Benezra R. Wojnarowicz PM, et al. Among authors: desai b. Cell Rep. 2019 Oct 1;29(1):62-75.e7. doi: 10.1016/j.celrep.2019.08.073. Cell Rep. 2019. PMID: 31577956 Free PMC article.
Anti-tumor effects of an ID antagonist with no observed acquired resistance.
Wojnarowicz PM, Escolano MG, Huang YH, Desai B, Chin Y, Shah R, Xu S, Yadav S, Yaklichkin S, Ouerfelli O, Soni RK, Philip J, Montrose DC, Healey JH, Rajasekhar VK, Garland WA, Ratiu J, Zhuang Y, Norton L, Rosen N, Hendrickson RC, Zhou XK, Iavarone A, Massague J, Dannenberg AJ, Lasorella A, Benezra R. Wojnarowicz PM, et al. Among authors: desai b. NPJ Breast Cancer. 2021 May 24;7(1):58. doi: 10.1038/s41523-021-00266-0. NPJ Breast Cancer. 2021. PMID: 34031428 Free PMC article.
Resistance to targeted therapies as a multifactorial, gradual adaptation to inhibitor specific selective pressures.
Vander Velde R, Yoon N, Marusyk V, Durmaz A, Dhawan A, Miroshnychenko D, Lozano-Peral D, Desai B, Balynska O, Poleszhuk J, Kenian L, Teng M, Abazeed M, Mian O, Tan AC, Haura E, Scott J, Marusyk A. Vander Velde R, et al. Among authors: desai b. Nat Commun. 2020 May 14;11(1):2393. doi: 10.1038/s41467-020-16212-w. Nat Commun. 2020. PMID: 32409712 Free PMC article.