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Clinical meaningfulness of subtle cognitive decline on longitudinal testing in preclinical AD.
Papp KV, Buckley R, Mormino E, Maruff P, Villemagne VL, Masters CL, Johnson KA, Rentz DM, Sperling RA, Amariglio RE; Collaborators from the Harvard Aging Brain Study, the Alzheimer's Disease Neuroimaging Initiative and the Australian Imaging, Biomarker and Lifestyle Study of Aging. Papp KV, et al. Alzheimers Dement. 2020 Mar;16(3):552-560. doi: 10.1016/j.jalz.2019.09.074. Epub 2020 Jan 4. Alzheimers Dement. 2020. PMID: 31759879 Free PMC article.
Study partner-reported decline identifies cognitive decline and dementia risk.
Nosheny RL, Jin C, Neuhaus J, Insel PS, Mackin RS, Weiner MW; Alzheimer’s Disease Neuroimaging Initiative investigators. Nosheny RL, et al. Ann Clin Transl Neurol. 2019 Dec;6(12):2448-2459. doi: 10.1002/acn3.50938. Epub 2019 Nov 13. Ann Clin Transl Neurol. 2019. PMID: 31721455 Free PMC article.
A Phase II Trial of Lutikizumab, an Anti-Interleukin-1α/β Dual Variable Domain Immunoglobulin, in Knee Osteoarthritis Patients With Synovitis.
Fleischmann RM, Bliddal H, Blanco FJ, Schnitzer TJ, Peterfy C, Chen S, Wang L, Feng S, Conaghan PG, Berenbaum F, Pelletier JP, Martel-Pelletier J, Vaeterlein O, Kaeley GS, Liu W, Kosloski MP, Levy G, Zhang L, Medema JK, Levesque MC. Fleischmann RM, et al. Arthritis Rheumatol. 2019 Jul;71(7):1056-1069. doi: 10.1002/art.40840. Epub 2019 Jun 7. Arthritis Rheumatol. 2019. PMID: 30653843 Free article. Clinical Trial.