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A specific secretion system mediates PPE41 transport in pathogenic mycobacteria.
Abdallah AM, Verboom T, Hannes F, Safi M, Strong M, Eisenberg D, Musters RJ, Vandenbroucke-Grauls CM, Appelmelk BJ, Luirink J, Bitter W. Abdallah AM, et al. Among authors: bitter w. Mol Microbiol. 2006 Nov;62(3):667-79. doi: 10.1111/j.1365-2958.2006.05409.x. Mol Microbiol. 2006. PMID: 17076665 Free article.
Type VII secretion--mycobacteria show the way.
Abdallah AM, Gey van Pittius NC, Champion PA, Cox J, Luirink J, Vandenbroucke-Grauls CM, Appelmelk BJ, Bitter W. Abdallah AM, et al. Among authors: bitter w. Nat Rev Microbiol. 2007 Nov;5(11):883-91. doi: 10.1038/nrmicro1773. Nat Rev Microbiol. 2007. PMID: 17922044
The mannose cap of mycobacterial lipoarabinomannan does not dominate the Mycobacterium-host interaction.
Appelmelk BJ, den Dunnen J, Driessen NN, Ummels R, Pak M, Nigou J, Larrouy-Maumus G, Gurcha SS, Movahedzadeh F, Geurtsen J, Brown EJ, Eysink Smeets MM, Besra GS, Willemsen PT, Lowary TL, van Kooyk Y, Maaskant JJ, Stoker NG, van der Ley P, Puzo G, Vandenbroucke-Grauls CM, Wieland CW, van der Poll T, Geijtenbeek TB, van der Sar AM, Bitter W. Appelmelk BJ, et al. Among authors: bitter w. Cell Microbiol. 2008 Apr;10(4):930-44. doi: 10.1111/j.1462-5822.2007.01097.x. Epub 2007 Dec 5. Cell Microbiol. 2008. PMID: 18070119
Mycobacterium marinum MMAR_2380, a predicted transmembrane acyltransferase, is essential for the presence of the mannose cap on lipoarabinomannan.
Driessen NN, Stoop EJM, Ummels R, Gurcha SS, Mishra AK, Larrouy-Maumus G, Nigou J, Gilleron M, Puzo G, Maaskant JJ, Sparrius M, Besra GS, Bitter W, Vandenbroucke-Grauls CMJE, Appelmelk BJ. Driessen NN, et al. Among authors: bitter w. Microbiology (Reading). 2010 Nov;156(Pt 11):3492-3502. doi: 10.1099/mic.0.037507-0. Epub 2010 Aug 5. Microbiology (Reading). 2010. PMID: 20688818 Free PMC article.
Conserved Pro-Glu (PE) and Pro-Pro-Glu (PPE) protein domains target LipY lipases of pathogenic mycobacteria to the cell surface via the ESX-5 pathway.
Daleke MH, Cascioferro A, de Punder K, Ummels R, Abdallah AM, van der Wel N, Peters PJ, Luirink J, Manganelli R, Bitter W. Daleke MH, et al. Among authors: bitter w. J Biol Chem. 2011 May 27;286(21):19024-34. doi: 10.1074/jbc.M110.204966. Epub 2011 Apr 6. J Biol Chem. 2011. PMID: 21471225 Free PMC article.
169 results