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Association of time-averaged serum uric acid level with clinicopathological information and long-term outcomes in patients with IgA nephropathy.
Weng M, Fu B, Zhuo Y, Lin J, Zou Z, Chen Y, Cui J, Li G, Chen C, Xu Y, Jiang D, Wan J. Weng M, et al. PeerJ. 2024 Apr 19;12:e17266. doi: 10.7717/peerj.17266. eCollection 2024. PeerJ. 2024. PMID: 38650643 Free PMC article.
RESULTS: Patients with high TA-SUA levels had higher levels of baseline SUA, blood urea nitrogen (BUN), triglycerides, serum C3 and serum C4 and were more likely to be male and have hypertension, proteinuria, poor renal function, and pathological injuries including …
RESULTS: Patients with high TA-SUA levels had higher levels of baseline SUA, blood urea nitrogen (BUN), triglycerides, serum C3 …
Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021.
GBD 2021 Diseases and Injuries Collaborators. GBD 2021 Diseases and Injuries Collaborators. Lancet. 2024 Apr 15:S0140-6736(24)00757-8. doi: 10.1016/S0140-6736(24)00757-8. Online ahead of print. Lancet. 2024. PMID: 38642570 Free article.
Clinical and pathological features of 52 patients with glomerulonephritis with dominant C3.
Wei J, Huang Y, Yuan S, Chen X, Fu X, Li Z, Li Y, Sun L, Liu H, Zhu X. Wei J, et al. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2024 Jan 28;49(1):75-83. doi: 10.11817/j.issn.1672-7347.2024.230328. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2024. PMID: 38615169 Free PMC article. Chinese, English.
RESULTS: The PIGN group had lower creatinine values (84.60 mumol/L vs179.62 mumol/L, P=0.001), lower complement C3 values (0.36 g/L vs0.74 g/L, P<0.001) at biopsy, and less severe pathological chronic lesions compared with the N-PIGN group. . …
RESULTS: The PIGN group had lower creatinine values (84.60 mumol/L vs179.62 mumol/L, P=0.001), lower complement C3 valu …
When you think you should transfuse…don't!
Gammon RR, Alvarez H, Masias C, Benitez N, Resto C. Gammon RR, et al. Lab Med. 2024 Apr 6:lmae024. doi: 10.1093/labmed/lmae024. Online ahead of print. Lab Med. 2024. PMID: 38581079
Admission laboratory test results were hemoglobin 6.6 g/dL, platelet count 287,000/muL, and white blood cell count 25,200/muL. Lactate dehydrogenase was elevated at 898 U/L, haptoglobin was markedly decreased (< 31 mg/dL), indirect bilirubin was elevated (5.3 mg/ …
Admission laboratory test results were hemoglobin 6.6 g/dL, platelet count 287,000/muL, and white blood cell count 25,200/muL. Lactat …
Abnormal biochemical indicators of neonatal inherited metabolic disease in carriers.
Guo F, Zhou L, Zhang F, Yu B, Yang Y, Liu Z. Guo F, et al. Orphanet J Rare Dis. 2024 Apr 4;19(1):145. doi: 10.1186/s13023-024-03138-5. Orphanet J Rare Dis. 2024. PMID: 38575986 Free PMC article.
Newborns underwent traditional biochemical screening at birth using blood staining and genomic sequencing of their stored blood staining using the NeoSeq Pro panel, which was able to detect 154 pathogenic genes and 86 diseases. ...In carriers associated with organic …
Newborns underwent traditional biochemical screening at birth using blood staining and genomic sequencing of their stored blood …
Enantiomer-Specific Cardiovascular Effects of the Ketone Body 3-Hydroxybutyrate.
Gopalasingam N, Moeslund N, Christensen KH, Berg-Hansen K, Seefeldt J, Homilius C, Nielsen EN, Dollerup MR, Alstrup Olsen AK, Johannsen M, Boedtkjer E, Møller N, Eiskjær H, Gormsen LC, Nielsen R, Wiggers H. Gopalasingam N, et al. J Am Heart Assoc. 2024 Apr 16;13(8):e033628. doi: 10.1161/JAHA.123.033628. Epub 2024 Apr 2. J Am Heart Assoc. 2024. PMID: 38563382 Free article. Clinical Trial.
The groups received 3-hour infusions of either D/L-3-OHB (racemic mixture), 100% L-3-OHB, 100% D-3-OHB, versus an isovolumic control. ...All three 3-OHB infusions increased 3-OHB levels (P<0.001). D/L-3-OHB and L-3-OHB increased CO by 2.7 L/m …
The groups received 3-hour infusions of either D/L-3-OHB (racemic mixture), 100% L-3-OHB, 100% D-3-OHB, versus an isovolumic c …
Drug target Mendelian randomization supports apolipoprotein C3-lowering for lipoprotein-lipid levels reductions and cardiovascular diseases prevention.
Gagnon E, Arsenault BJ. Gagnon E, et al. Atherosclerosis. 2024 Apr;391:117501. doi: 10.1016/j.atherosclerosis.2024.117501. Epub 2024 Feb 28. Atherosclerosis. 2024. PMID: 38547584
We used drug target Mendelian randomization (MR) to assess the effect of genetically predicted decrease in apoC3 blood protein levels on cardiometabolic traits and diseases. METHODS: We quantified lifelong reductions in apoC3 blood levels by selecting all genome wid …
We used drug target Mendelian randomization (MR) to assess the effect of genetically predicted decrease in apoC3 blood protein levels …
C1q and HBHA-specific IL-13 levels as surrogate plasma biomarkers for monitoring tuberculosis treatment efficacy: a cross-sectional cohort study in Paraguay.
Russomando G, Sanabria D, Díaz Acosta CC, Rojas L, Franco L, Arenas R, Delogu G, Ndiaye MDB, Bayaa R, Rakotosamimanana N, Goletti D, Hoffmann J. Russomando G, et al. Front Immunol. 2024 Mar 13;15:1308015. doi: 10.3389/fimmu.2024.1308015. eCollection 2024. Front Immunol. 2024. PMID: 38545118 Free PMC article.
At each timepoint plasma levels of IFN-y, 17 pro- and anti-inflammatory cytokines/chemokines and complement factors C1q, C3 and C4 were assessed in unstimulated and Mtb-specific stimulated whole blood samples using QuantiFERON-TB gold plus and recombinant Mycobacter …
At each timepoint plasma levels of IFN-y, 17 pro- and anti-inflammatory cytokines/chemokines and complement factors C1q, C3 and C4 we …
Correlation between the cardiometabolic index and arteriosclerosis in patients with type 2 diabetes mellitus.
Tang C, Pang T, Dang C, Liang H, Wu J, Shen X, Wang L, Luo R, Lan H, Zhang P. Tang C, et al. BMC Cardiovasc Disord. 2024 Mar 27;24(1):186. doi: 10.1186/s12872-024-03853-8. BMC Cardiovasc Disord. 2024. PMID: 38539102 Free PMC article.
METHODS: This study involved 2243 patients with T2DM. The CMI was derived by dividing the triglyceride level (mmol/L) by the high-density lipoprotein level (mmol/L) and then multiplying the quotient by the waist-to-height ratio. Multivariate logistic regression was …
METHODS: This study involved 2243 patients with T2DM. The CMI was derived by dividing the triglyceride level (mmol/L) by the high-den …
Effect of silk fibroin microparticles on cellular immunity and liver of gilthead seabream (Sparus aurata L.) with and without experimental skin injuries.
Albaladejo-Riad N, Espinosa-Ruiz C, Esteban MÁ. Albaladejo-Riad N, et al. J Anim Physiol Anim Nutr (Berl). 2024 Mar 14. doi: 10.1111/jpn.13950. Online ahead of print. J Anim Physiol Anim Nutr (Berl). 2024. PMID: 38483166
Our results showed that experimental wounds affect both cellular immunity (by decreasing leucocyte respiratory burst and peroxidase activity) and altered liver histology (by inducing vascularisation and congestion of blood vessels). In addition, it influences the expressio …
Our results showed that experimental wounds affect both cellular immunity (by decreasing leucocyte respiratory burst and peroxidase activity …
1,574 results