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Page 1
In-flow photooxygenation of aminothienopyridinones generates iminopyridinedione PTP4A3 phosphatase inhibitors.
Org Biomol Chem. 2019 Feb 27;17(9):2448-2466. doi: 10.1039/c9ob00025a.
Org Biomol Chem. 2019.
PMID: 30746541
Next-Generation Cell-Active Inhibitors of the Undrugged Oncogenic PTP4A3 Phosphatase.
Lazo JS, Blanco IK, Tasker NR, Rastelli EJ, Burnett JC, Garrott SR, Hart DJ, McCloud RL, Hsu KL, Wipf P, Sharlow ER.
Lazo JS, et al. Among authors: blanco ik.
J Pharmacol Exp Ther. 2019 Dec;371(3):652-662. doi: 10.1124/jpet.119.262188. Epub 2019 Oct 10.
J Pharmacol Exp Ther. 2019.
PMID: 31601683
Free PMC article.
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A three-dimensional dementia model reveals spontaneous cell cycle re-entry and a senescence-associated secretory phenotype.
Porterfield V, Khan SS, Foff EP, Koseoglu MM, Blanco IK, Jayaraman S, Lien E, McConnell MJ, Bloom GS, Lazo JS, Sharlow ER.
Porterfield V, et al. Among authors: blanco ik.
Neurobiol Aging. 2020 Jun;90:125-134. doi: 10.1016/j.neurobiolaging.2020.02.011. Epub 2020 Feb 19.
Neurobiol Aging. 2020.
PMID: 32184029
Free PMC article.
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Structure of the Complex of an Iminopyridinedione Protein Tyrosine Phosphatase 4A3 Phosphatase Inhibitor with Human Serum Albumin.
Czub MP, Boulton AM, Rastelli EJ, Tasker NR, Maskrey TS, Blanco IK, McQueeney KE, Bushweller JH, Minor W, Wipf P, Sharlow ER, Lazo JS.
Czub MP, et al. Among authors: blanco ik.
Mol Pharmacol. 2020 Dec;98(6):648-657. doi: 10.1124/molpharm.120.000131. Epub 2020 Sep 25.
Mol Pharmacol. 2020.
PMID: 32978326
Free PMC article.
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A chemical genetics approach identifies PTP4A3 as a regulator of colon cancer cell adhesion.
McQueeney KE, Salamoun JM, Ahn JG, Pekic P, Blanco IK, Struckman HL, Sharlow ER, Wipf P, Lazo JS.
McQueeney KE, et al. Among authors: blanco ik.
FASEB J. 2018 Oct;32(10):5661-5673. doi: 10.1096/fj.201701446R. Epub 2018 May 10.
FASEB J. 2018.
PMID: 29746167
Free PMC article.
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