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Natural and vaccine-mediated immunity to Salmonella Typhimurium is impaired by the helminth Nippostrongylus brasiliensis.
Bobat S, Darby M, Mrdjen D, Cook C, Logan E, Auret J, Jones E, Schnoeller C, Flores-Langarica A, Ross EA, Vira A, López-Macías C, Henderson IR, Alexander J, Brombacher F, Horsnell WG, Cunningham AF. Bobat S, et al. PLoS Negl Trop Dis. 2014 Dec 4;8(12):e3341. doi: 10.1371/journal.pntd.0003341. eCollection 2014 Dec. PLoS Negl Trop Dis. 2014. PMID: 25474738 Free PMC article.
CD31 is required on CD4+ T cells to promote T cell survival during Salmonella infection.
Ross EA, Coughlan RE, Flores-Langarica A, Bobat S, Marshall JL, Hussain K, Charlesworth J, Abhyankar N, Hitchcock J, Gil C, López-Macías C, Henderson IR, Khan M, Watson SP, MacLennan IC, Buckley CD, Cunningham AF. Ross EA, et al. Among authors: bobat s. J Immunol. 2011 Aug 15;187(4):1553-65. doi: 10.4049/jimmunol.1000502. Epub 2011 Jul 6. J Immunol. 2011. PMID: 21734076 Free PMC article.
Soluble flagellin, FliC, induces an Ag-specific Th2 response, yet promotes T-bet-regulated Th1 clearance of Salmonella typhimurium infection.
Bobat S, Flores-Langarica A, Hitchcock J, Marshall JL, Kingsley RA, Goodall M, Gil-Cruz C, Serre K, Leyton DL, Letran SE, Gaspal F, Chester R, Chamberlain JL, Dougan G, López-Macías C, Henderson IR, Alexander J, MacLennan IC, Cunningham AF. Bobat S, et al. Eur J Immunol. 2011 Jun;41(6):1606-18. doi: 10.1002/eji.201041089. Epub 2011 May 10. Eur J Immunol. 2011. PMID: 21469112 Free article.
T-zone localized monocyte-derived dendritic cells promote Th1 priming to Salmonella.
Flores-Langarica A, Marshall JL, Bobat S, Mohr E, Hitchcock J, Ross EA, Coughlan RE, Khan M, Van Rooijen N, Henderson IR, Maclennan IC, Cunningham AF. Flores-Langarica A, et al. Among authors: bobat s. Eur J Immunol. 2011 Sep;41(9):2654-65. doi: 10.1002/eji.201141440. Epub 2011 Aug 4. Eur J Immunol. 2011. PMID: 21630252 Free article.
Bacterial infections and vaccines.
Bobat S, Cunningham AF. Bobat S, et al. Adv Exp Med Biol. 2014;828:75-98. doi: 10.1007/978-1-4939-1489-0_4. Adv Exp Med Biol. 2014. PMID: 25253028 Review. No abstract available.
Systemic flagellin immunization stimulates mucosal CD103+ dendritic cells and drives Foxp3+ regulatory T cell and IgA responses in the mesenteric lymph node.
Flores-Langarica A, Marshall JL, Hitchcock J, Cook C, Jobanputra J, Bobat S, Ross EA, Coughlan RE, Henderson IR, Uematsu S, Akira S, Cunningham AF. Flores-Langarica A, et al. Among authors: bobat s. J Immunol. 2012 Dec 15;189(12):5745-54. doi: 10.4049/jimmunol.1202283. Epub 2012 Nov 14. J Immunol. 2012. PMID: 23152564
32 results