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The metabotropic glutamate receptor 4-positive allosteric modulator VU0364770 produces efficacy alone and in combination with L-DOPA or an adenosine 2A antagonist in preclinical rodent models of Parkinson's disease.
Jones CK, Bubser M, Thompson AD, Dickerson JW, Turle-Lorenzo N, Amalric M, Blobaum AL, Bridges TM, Morrison RD, Jadhav S, Engers DW, Italiano K, Bode J, Daniels JS, Lindsley CW, Hopkins CR, Conn PJ, Niswender CM. Jones CK, et al. Among authors: bode j. J Pharmacol Exp Ther. 2012 Feb;340(2):404-21. doi: 10.1124/jpet.111.187443. Epub 2011 Nov 16. J Pharmacol Exp Ther. 2012. PMID: 22088953 Free PMC article.
Novel allosteric agonists of M1 muscarinic acetylcholine receptors induce brain region-specific responses that correspond with behavioral effects in animal models.
Digby GJ, Noetzel MJ, Bubser M, Utley TJ, Walker AG, Byun NE, Lebois EP, Xiang Z, Sheffler DJ, Cho HP, Davis AA, Nemirovsky NE, Mennenga SE, Camp BW, Bimonte-Nelson HA, Bode J, Italiano K, Morrison R, Daniels JS, Niswender CM, Olive MF, Lindsley CW, Jones CK, Conn PJ. Digby GJ, et al. Among authors: bode j. J Neurosci. 2012 Jun 20;32(25):8532-44. doi: 10.1523/JNEUROSCI.0337-12.2012. J Neurosci. 2012. PMID: 22723693 Free PMC article.
Soluble urokinase plasminogen activator receptor levels predict survival in patients with portal hypertension undergoing TIPS.
Loosen SH, Benz F, Mohr R, Reuken PA, Wirtz TH, Junker L, Jansen C, Meyer C, Praktiknjo M, Wree A, Reißing J, Demir M, Gu W, Vucur M, Schierwagen R, Stallmach A, Kunstein A, Bode J, Trautwein C, Tacke F, Luedde T, Bruns T, Trebicka J, Roderburg C. Loosen SH, et al. Among authors: bode j. JHEP Rep. 2024 Mar 4;6(5):101054. doi: 10.1016/j.jhepr.2024.101054. eCollection 2024 May. JHEP Rep. 2024. PMID: 38681861 Free PMC article.
The thrombin receptor PAR4 supports visceral adipose tissue inflammation.
Kleeschulte S, Fischinger V, Öhlke L, Bode J, Kamler M, Dobrev D, Grandoch M, Fender AC. Kleeschulte S, et al. Among authors: bode j. Naunyn Schmiedebergs Arch Pharmacol. 2024 Apr 23. doi: 10.1007/s00210-024-03097-5. Online ahead of print. Naunyn Schmiedebergs Arch Pharmacol. 2024. PMID: 38652276
Myotubularin-related-protein-7 inhibits mutant (G12V) K-RAS by direct interaction.
Weidner P, Saar D, Söhn M, Schroeder T, Yu Y, Zöllner FG, Ponelies N, Zhou X, Zwicky A, Rohrbacher FN, Pattabiraman VR, Tanriver M, Bauer A, Ahmed H, Ametamey SM, Riffel P, Seger R, Bode JW, Wade RC, Ebert MPA, Kragelund BB, Burgermeister E. Weidner P, et al. Among authors: bode jw. Cancer Lett. 2024 Apr 28;588:216783. doi: 10.1016/j.canlet.2024.216783. Epub 2024 Mar 9. Cancer Lett. 2024. PMID: 38462034 Free article.
Nationwide quality assurance of high-throughput diagnostic molecular testing during the SARS-CoV-2 pandemic: role of the Belgian National Reference Centre.
Janssen R, Cuypers L, Laenen L, Keyaerts E, Beuselinck K, Janssenswillen S, Slechten B, Bode J, Wollants E, Van Laethem K, Rector A, Bloemen M, Sijmons A, de Schaetzen N, Capron A, Van Baelen K, Pascal T, Vermeiren C, Bureau F, Vandesompele J, De Smet P, Uten W, Malonne H, Kerkhofs P, De Cock J, Matheeussen V, Verhasselt B, Gillet L, Detry G, Bearzatto B, Degosserie J, Henin C, Pairoux G; COVID-19 Genomics Belgium Consortium; Maes P, Van Ranst M, Lagrou K, Dequeker E, André E. Janssen R, et al. Among authors: bode j. Virol J. 2024 Feb 10;21(1):40. doi: 10.1186/s12985-024-02308-y. Virol J. 2024. PMID: 38341597 Free PMC article. Review.
T-cell immunophenotype correlations with cortical thickness and white matter microstructure in bipolar disorder.
Escelsior A, Inuggi A, Sterlini B, Bovio A, Marenco G, Bode J, Favilla L, Tardito S, Altosole T, Pereira da Silva B, Fenoglio D, Filaci G, Amore M, Serafini G. Escelsior A, et al. Among authors: bode j. J Affect Disord. 2024 Mar 1;348:179-190. doi: 10.1016/j.jad.2023.12.054. Epub 2023 Dec 26. J Affect Disord. 2024. PMID: 38154587 Free article.
681 results