Bodmer WF - Search Results

1

Variants at the secretory phospholipase A2 (PLA2G2A) locus: analysis of associations with familial adenomatous polyposis and sporadic colorectal tumours.

Tomlinson IP, Beck NE, Neale K, Bodmer WF. Tomlinson IP, et al. Among authors: bodmer wf. Ann Hum Genet. 1996 Sep;60(5):369-76. doi: 10.1111/j.1469-1809.1996.tb00434.x. Ann Hum Genet. 1996. PMID: 8912789

2

The type of somatic mutation at APC in familial adenomatous polyposis is determined by the site of the germline mutation: a new facet to Knudson's 'two-hit' hypothesis.

Lamlum H, Ilyas M, Rowan A, Clark S, Johnson V, Bell J, Frayling I, Efstathiou J, Pack K, Payne S, Roylance R, Gorman P, Sheer D, Neale K, Phillips R, Talbot I, Bodmer W, Tomlinson I. Lamlum H, et al. Nat Med. 1999 Sep;5(9):1071-5. doi: 10.1038/12511. Nat Med. 1999. PMID: 10470088

3

Germline APC variants in patients with multiple colorectal adenomas, with evidence for the particular importance of E1317Q.

Lamlum H, Al Tassan N, Jaeger E, Frayling I, Sieber O, Reza FB, Eckert M, Rowan A, Barclay E, Atkin W, Williams C, Gilbert J, Cheadle J, Bell J, Houlston R, Bodmer W, Sampson J, Tomlinson I. Lamlum H, et al. Hum Mol Genet. 2000 Sep 22;9(15):2215-21. doi: 10.1093/oxfordjournals.hmg.a018912. Hum Mol Genet. 2000. PMID: 11001924

4

Whole-gene APC deletions cause classical familial adenomatous polyposis, but not attenuated polyposis or "multiple" colorectal adenomas.

Sieber OM, Lamlum H, Crabtree MD, Rowan AJ, Barclay E, Lipton L, Hodgson S, Thomas HJ, Neale K, Phillips RK, Farrington SM, Dunlop MG, Mueller HJ, Bisgaard ML, Bulow S, Fidalgo P, Albuquerque C, Scarano MI, Bodmer W, Tomlinson IP, Heinimann K. Sieber OM, et al. Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):2954-8. doi: 10.1073/pnas.042699199. Epub 2002 Feb 26. Proc Natl Acad Sci U S A. 2002. PMID: 11867715 Free PMC article.

5

Mutations in DPC4 (SMAD4) cause juvenile polyposis syndrome, but only account for a minority of cases.

Houlston R, Bevan S, Williams A, Young J, Dunlop M, Rozen P, Eng C, Markie D, Woodford-Richens K, Rodriguez-Bigas MA, Leggett B, Neale K, Phillips R, Sheridan E, Hodgson S, Iwama T, Eccles D, Bodmer W, Tomlinson I. Houlston R, et al. Hum Mol Genet. 1998 Nov;7(12):1907-12. doi: 10.1093/hmg/7.12.1907. Hum Mol Genet. 1998. PMID: 9811934

6

Genetic mapping of hereditary mixed polyposis syndrome to chromosome 6q.

Thomas HJ, Whitelaw SC, Cottrell SE, Murday VA, Tomlinson IP, Markie D, Jones T, Bishop DT, Hodgson SV, Sheer D, Northover JM, Talbot IC, Solomon E, Bodmer WF. Thomas HJ, et al. Among authors: bodmer wf. Am J Hum Genet. 1996 Apr;58(4):770-6. Am J Hum Genet. 1996. PMID: 8644741 Free PMC article.

7

Chromosome 11q in sporadic colorectal carcinoma: patterns of allele loss and their significance for tumorigenesis.

Tomlinson IP, Bodmer WF. Tomlinson IP, et al. Among authors: bodmer wf. J Clin Pathol. 1996 May;49(5):386-90. doi: 10.1136/jcp.49.5.386. J Clin Pathol. 1996. PMID: 8707952 Free PMC article.

8

A modifying locus for familial adenomatous polyposis may be present on chromosome 1p35-p36.

Tomlinson IP, Neale K, Talbot IC, Spigelman AD, Williams CB, Phillips RK, Bodmer WF. Tomlinson IP, et al. Among authors: bodmer wf. J Med Genet. 1996 Apr;33(4):268-73. doi: 10.1136/jmg.33.4.268. J Med Genet. 1996. PMID: 8730279 Free PMC article.

9

Population genetics of tumours.

Bodmer WF, Tomlinson I. Bodmer WF, et al. Ciba Found Symp. 1996;197:181-9; discussion 189-93. doi: 10.1002/9780470514887.ch10. Ciba Found Symp. 1996. PMID: 8827374 Review.

10

Testing candidate loci on chromosomes 1 and 6 for genetic linkage to Peutz-Jeghers' disease.

Tomlinson IP, Olschwang S, Abelovitch D, Nakamura Y, Bodmer WF, Thomas G, Markie D. Tomlinson IP, et al. Among authors: bodmer wf. Ann Hum Genet. 1996 Sep;60(5):377-84. doi: 10.1111/j.1469-1809.1996.tb00435.x. Ann Hum Genet. 1996. PMID: 8912790

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