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TP53 mutations in myelodysplastic syndromes and secondary AML confer an immunosuppressive phenotype.
Sallman DA, McLemore AF, Aldrich AL, Komrokji RS, McGraw KL, Dhawan A, Geyer S, Hou HA, Eksioglu EA, Sullivan A, Warren S, MacBeth KJ, Meggendorfer M, Haferlach T, Boettcher S, Ebert BL, Al Ali NH, Lancet JE, Cleveland JL, Padron E, List AF. Sallman DA, et al. Among authors: boettcher s. Blood. 2020 Dec 10;136(24):2812-2823. doi: 10.1182/blood.2020006158. Blood. 2020. PMID: 32730593 Free PMC article.
Clonal Hematopoiesis of Indeterminate Potential.
Boettcher S, Ebert BL. Boettcher S, et al. J Clin Oncol. 2019 Feb 10;37(5):419-422. doi: 10.1200/JCO.2018.79.3588. Epub 2018 Dec 27. J Clin Oncol. 2019. PMID: 30589599 No abstract available.
A dominant-negative effect drives selection of TP53 missense mutations in myeloid malignancies.
Boettcher S, Miller PG, Sharma R, McConkey M, Leventhal M, Krivtsov AV, Giacomelli AO, Wong W, Kim J, Chao S, Kurppa KJ, Yang X, Milenkowic K, Piccioni F, Root DE, Rücker FG, Flamand Y, Neuberg D, Lindsley RC, Jänne PA, Hahn WC, Jacks T, Döhner H, Armstrong SA, Ebert BL. Boettcher S, et al. Science. 2019 Aug 9;365(6453):599-604. doi: 10.1126/science.aax3649. Science. 2019. PMID: 31395785 Free PMC article.
An induced pluripotent stem cell model of Fanconi anemia reveals mechanisms of p53-driven progenitor cell differentiation.
Marion W, Boettcher S, Ruiz-Torres S, Lummertz da Rocha E, Lundin V, Morris V, Chou S, Zhao AM, Kubaczka C, Aumais O, Zhang Y, Shimamura A, Schlaeger TM, North TE, Ebert BL, Wells SI, Daley GQ, Rowe RG. Marion W, et al. Among authors: boettcher s. Blood Adv. 2020 Oct 13;4(19):4679-4692. doi: 10.1182/bloodadvances.2020001593. Blood Adv. 2020. PMID: 33002135 Free PMC article.
Wnt to the rescue! A new role in granulopoiesis.
Boettcher S. Boettcher S. Blood. 2020 Nov 26;136(22):2487-2489. doi: 10.1182/blood.2020008667. Blood. 2020. PMID: 33242329 Free article. No abstract available.
197 results