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Page 1
Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing.
Yin H, Song CQ, Suresh S, Wu Q, Walsh S, Rhym LH, Mintzer E, Bolukbasi MF, Zhu LJ, Kauffman K, Mou H, Oberholzer A, Ding J, Kwan SY, Bogorad RL, Zatsepin T, Koteliansky V, Wolfe SA, Xue W, Langer R, Anderson DG. Yin H, et al. Among authors: bolukbasi mf. Nat Biotechnol. 2017 Dec;35(12):1179-1187. doi: 10.1038/nbt.4005. Epub 2017 Nov 13. Nat Biotechnol. 2017. PMID: 29131148 Free PMC article.
Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo.
Yin H, Song CQ, Dorkin JR, Zhu LJ, Li Y, Wu Q, Park A, Yang J, Suresh S, Bizhanova A, Gupta A, Bolukbasi MF, Walsh S, Bogorad RL, Gao G, Weng Z, Dong Y, Koteliansky V, Wolfe SA, Langer R, Xue W, Anderson DG. Yin H, et al. Among authors: bolukbasi mf. Nat Biotechnol. 2016 Mar;34(3):328-33. doi: 10.1038/nbt.3471. Epub 2016 Feb 1. Nat Biotechnol. 2016. PMID: 26829318 Free PMC article.
Enhanced Cas12a editing in mammalian cells and zebrafish.
Liu P, Luk K, Shin M, Idrizi F, Kwok S, Roscoe B, Mintzer E, Suresh S, Morrison K, Frazão JB, Bolukbasi MF, Ponnienselvan K, Luban J, Zhu LJ, Lawson ND, Wolfe SA. Liu P, et al. Among authors: bolukbasi mf. Nucleic Acids Res. 2019 May 7;47(8):4169-4180. doi: 10.1093/nar/gkz184. Nucleic Acids Res. 2019. PMID: 30892626 Free PMC article.
SIR proteins create compact heterochromatin fibers.
Swygert SG, Senapati S, Bolukbasi MF, Wolfe SA, Lindsay S, Peterson CL. Swygert SG, et al. Among authors: bolukbasi mf. Proc Natl Acad Sci U S A. 2018 Dec 4;115(49):12447-12452. doi: 10.1073/pnas.1810647115. Epub 2018 Nov 19. Proc Natl Acad Sci U S A. 2018. PMID: 30455303 Free PMC article.
miR-1289 and "Zipcode"-like Sequence Enrich mRNAs in Microvesicles.
Bolukbasi MF, Mizrak A, Ozdener GB, Madlener S, Ströbel T, Erkan EP, Fan JB, Breakefield XO, Saydam O. Bolukbasi MF, et al. Mol Ther Nucleic Acids. 2012 Feb 7;1(2):e10. doi: 10.1038/mtna.2011.2. Mol Ther Nucleic Acids. 2012. PMID: 23344721 Free PMC article.