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Mechanisms of Bone Morphogenetic Protein 2 in Respiratory Diseases.
Wen Y, Zheng Y, Hua S, Li T, Bi X, Lu Q, Li M, Sun S. Wen Y, et al. Curr Allergy Asthma Rep. 2024 Oct 28;25(1):1. doi: 10.1007/s11882-024-01181-7. Curr Allergy Asthma Rep. 2024. PMID: 39466470 Review.
PURPOSE OF REVIEW: Bone morphogenetic protein 2 (BMP2) belongs to the transforming growth factor-beta (TGF-beta) superfamily and plays an important role in regulating embryonic development, angiogenesis, osteogenic differentiation, …
PURPOSE OF REVIEW: Bone morphogenetic protein 2 (BMP2) belongs to the transforming growth factor-beta (TG …
Bone morphogenetic protein-2 stimulates angiogenesis in developing tumors.
Langenfeld EM, Langenfeld J. Langenfeld EM, et al. Mol Cancer Res. 2004 Mar;2(3):141-9. Mol Cancer Res. 2004. PMID: 15037653
Bone Morphogenetic Protein-2 (BMP-2) is highly overexpressed in the majority of patient-derived lung carcinomas. ...This study reveals that BMP-2 enhanced the angiogenic response in developing tumors. Furthermore, these data suggest that …
Bone Morphogenetic Protein-2 (BMP-2) is highly overexpressed in the majority of patient-derived lung carcinomas. …
Bone morphogenetic protein 2 (BMP-2) and induction of tumor angiogenesis.
Raida M, Clement JH, Leek RD, Ameri K, Bicknell R, Niederwieser D, Harris AL. Raida M, et al. J Cancer Res Clin Oncol. 2005 Nov;131(11):741-50. doi: 10.1007/s00432-005-0024-1. Epub 2005 Nov 1. J Cancer Res Clin Oncol. 2005. PMID: 16136355
In the murine breast cancer xenograft model, human MCF-7 cells with stable overexpression of BMP-2 developed vascularized tumors while empty vector control MCF-7 cells failed to form tumors. CONCLUSIONS: We conclude that activation of the BMP pathway by BMP-2 …
In the murine breast cancer xenograft model, human MCF-7 cells with stable overexpression of BMP-2 developed vascularized tumors …
Mild heat stress enhances angiogenesis in a co-culture system consisting of primary human osteoblasts and outgrowth endothelial cells.
Li M, Fuchs S, Böse T, Schmidt H, Hofmann A, Tonak M, Unger R, Kirkpatrick CJ. Li M, et al. Tissue Eng Part C Methods. 2014 Apr;20(4):328-39. doi: 10.1089/ten.TEC.2013.0087. Epub 2013 Oct 5. Tissue Eng Part C Methods. 2014. PMID: 23998634 Free PMC article.
As shown by real-time polymerase chain reaction (PCR), the expression of vascular endothelial growth factor (VEGF), angiopoietin-1 (Ang-1), angiopoietin-2 (Ang-2), and tumor necrosis factor-alpha was up-regulated in MHS-treated co-cultures 24 h post-treatment. ...Ne …
As shown by real-time polymerase chain reaction (PCR), the expression of vascular endothelial growth factor (VEGF), angiopoietin-1 (A …