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Spermine oxidase maintains basal skeletal muscle gene expression and fiber size and is strongly repressed by conditions that cause skeletal muscle atrophy.
Bongers KS, Fox DK, Kunkel SD, Stebounova LV, Murry DJ, Pufall MA, Ebert SM, Dyle MC, Bullard SA, Dierdorff JM, Adams CM. Bongers KS, et al. Am J Physiol Endocrinol Metab. 2015 Jan 15;308(2):E144-58. doi: 10.1152/ajpendo.00472.2014. Epub 2014 Nov 18. Am J Physiol Endocrinol Metab. 2015. PMID: 25406264 Free PMC article.
Identification and Small Molecule Inhibition of an Activating Transcription Factor 4 (ATF4)-dependent Pathway to Age-related Skeletal Muscle Weakness and Atrophy.
Ebert SM, Dyle MC, Bullard SA, Dierdorff JM, Murry DJ, Fox DK, Bongers KS, Lira VA, Meyerholz DK, Talley JJ, Adams CM. Ebert SM, et al. Among authors: bongers ks. J Biol Chem. 2015 Oct 16;290(42):25497-511. doi: 10.1074/jbc.M115.681445. Epub 2015 Sep 3. J Biol Chem. 2015. PMID: 26338703 Free PMC article.
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