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Structure and characterization of a high affinity C5a monoclonal antibody that blocks binding to C5aR1 and C5aR2 receptors.
Colley CS, Popovic B, Sridharan S, Debreczeni JE, Hargeaves D, Fung M, An LL, Edwards B, Arnold J, England E, Eghobamien L, Sivars U, Flavell L, Renshaw J, Wickson K, Warrener P, Zha J, Bonnell J, Woods R, Wilkinson T, Dobson C, Vaughan TJ. Colley CS, et al. Among authors: bonnell j. MAbs. 2018 Jan;10(1):104-117. doi: 10.1080/19420862.2017.1384892. Epub 2017 Oct 24. MAbs. 2018. PMID: 28952876 Free PMC article.
Identification of broadly protective human antibodies to Pseudomonas aeruginosa exopolysaccharide Psl by phenotypic screening.
DiGiandomenico A, Warrener P, Hamilton M, Guillard S, Ravn P, Minter R, Camara MM, Venkatraman V, Macgill RS, Lin J, Wang Q, Keller AE, Bonnell JC, Tomich M, Jermutus L, McCarthy MP, Melnick DA, Suzich JA, Stover CK. DiGiandomenico A, et al. Among authors: bonnell jc. J Exp Med. 2012 Jul 2;209(7):1273-87. doi: 10.1084/jem.20120033. Epub 2012 Jun 25. J Exp Med. 2012. PMID: 22734046 Free PMC article.
A multifunctional bispecific antibody protects against Pseudomonas aeruginosa.
DiGiandomenico A, Keller AE, Gao C, Rainey GJ, Warrener P, Camara MM, Bonnell J, Fleming R, Bezabeh B, Dimasi N, Sellman BR, Hilliard J, Guenther CM, Datta V, Zhao W, Gao C, Yu XQ, Suzich JA, Stover CK. DiGiandomenico A, et al. Among authors: bonnell j. Sci Transl Med. 2014 Nov 12;6(262):262ra155. doi: 10.1126/scitranslmed.3009655. Sci Transl Med. 2014. PMID: 25391481
Enhancement of antibody functions through Fc multiplications.
Wang Q, Chen Y, Pelletier M, Cvitkovic R, Bonnell J, Chang CY, Koksal AC, O'Connor E, Gao X, Yu XQ, Wu H, Stover CK, Dall'Acqua WF, Xiao X. Wang Q, et al. Among authors: bonnell j. MAbs. 2017 Apr;9(3):393-403. doi: 10.1080/19420862.2017.1281505. Epub 2017 Jan 19. MAbs. 2017. PMID: 28102754 Free PMC article.
Anti-LPS antibodies protect against Klebsiella pneumoniae by empowering neutrophil-mediated clearance without neutralizing TLR4.
Cohen TS, Pelletier M, Cheng L, Pennini ME, Bonnell J, Cvitkovic R, Chang CS, Xiao X, Cameroni E, Corti D, Semenova E, Warrener P, Sellman BR, Suzich J, Wang Q, Stover CK. Cohen TS, et al. Among authors: bonnell j. JCI Insight. 2017 May 4;2(9):e92774. doi: 10.1172/jci.insight.92774. eCollection 2017 May 4. JCI Insight. 2017. PMID: 28469079 Free PMC article.
Immune stealth-driven O2 serotype prevalence and potential for therapeutic antibodies against multidrug resistant Klebsiella pneumoniae.
Pennini ME, De Marco A, Pelletier M, Bonnell J, Cvitkovic R, Beltramello M, Cameroni E, Bianchi S, Zatta F, Zhao W, Xiao X, Camara MM, DiGiandomenico A, Semenova E, Lanzavecchia A, Warrener P, Suzich J, Wang Q, Corti D, Stover CK. Pennini ME, et al. Among authors: bonnell j. Nat Commun. 2017 Dec 8;8(1):1991. doi: 10.1038/s41467-017-02223-7. Nat Commun. 2017. PMID: 29222409 Free PMC article.
Staphylococcus aureus drives expansion of low-density neutrophils in diabetic mice.
Cohen TS, Takahashi V, Bonnell J, Tovchigrechko A, Chaerkady R, Yu W, Jones-Nelson O, Lee Y, Raja R, Hess S, Stover CK, Worthington JJ, Travis MA, Sellman BR. Cohen TS, et al. Among authors: bonnell j. J Clin Invest. 2019 Apr 15;129(5):2133-2144. doi: 10.1172/JCI126938. eCollection 2019 Apr 15. J Clin Invest. 2019. PMID: 30985291 Free PMC article.
81 results