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Collagens at a glance.
Kadler KE, Baldock C, Bella J, Boot-Handford RP. Kadler KE, et al. J Cell Sci. 2007 Jun 15;120(Pt 12):1955-8. doi: 10.1242/jcs.03453. J Cell Sci. 2007. PMID: 17550969 Review. No abstract available.
Reduced cell proliferation and increased apoptosis are significant pathological mechanisms in a murine model of mild pseudoachondroplasia resulting from a mutation in the C-terminal domain of COMP.
Piróg-Garcia KA, Meadows RS, Knowles L, Heinegård D, Thornton DJ, Kadler KE, Boot-Handford RP, Briggs MD. Piróg-Garcia KA, et al. Hum Mol Genet. 2007 Sep 1;16(17):2072-88. doi: 10.1093/hmg/ddm155. Epub 2007 Jun 22. Hum Mol Genet. 2007. PMID: 17588960 Free PMC article.
Targeted induction of endoplasmic reticulum stress induces cartilage pathology.
Rajpar MH, McDermott B, Kung L, Eardley R, Knowles L, Heeran M, Thornton DJ, Wilson R, Bateman JF, Poulsom R, Arvan P, Kadler KE, Briggs MD, Boot-Handford RP. Rajpar MH, et al. PLoS Genet. 2009 Oct;5(10):e1000691. doi: 10.1371/journal.pgen.1000691. Epub 2009 Oct 16. PLoS Genet. 2009. PMID: 19834559 Free PMC article.
Collagen XXVII organises the pericellular matrix in the growth plate.
Plumb DA, Ferrara L, Torbica T, Knowles L, Mironov A Jr, Kadler KE, Briggs MD, Boot-Handford RP. Plumb DA, et al. PLoS One. 2011;6(12):e29422. doi: 10.1371/journal.pone.0029422. Epub 2011 Dec 19. PLoS One. 2011. PMID: 22206015 Free PMC article.
Decreased chondrocyte proliferation and dysregulated apoptosis in the cartilage growth plate are key features of a murine model of epiphyseal dysplasia caused by a matn3 mutation.
Leighton MP, Nundlall S, Starborg T, Meadows RS, Suleman F, Knowles L, Wagener R, Thornton DJ, Kadler KE, Boot-Handford RP, Briggs MD. Leighton MP, et al. Hum Mol Genet. 2007 Jul 15;16(14):1728-41. doi: 10.1093/hmg/ddm121. Epub 2007 May 21. Hum Mol Genet. 2007. PMID: 17517694 Free PMC article.
122 results