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Propionamide Derivatives as Dual μ-Opioid Receptor Agonists and σ1 Receptor Antagonists for the Treatment of Pain.
García M, Llorente V, Garriga L, Christmann U, Rodríguez-Escrich S, Virgili M, Fernández B, Bordas M, Ayet E, Burgueño J, Pujol M, Dordal A, Portillo-Salido E, Gris G, Vela JM, Almansa C. García M, et al. Among authors: bordas m. J Med Chem. 2021 Jul 22;64(14):10139-10154. doi: 10.1021/acs.jmedchem.1c00417. Epub 2021 Jul 8. J Med Chem. 2021. PMID: 34236190
EOMES is essential for antitumor activity of CD8+ T cells in chronic lymphocytic leukemia.
Llaó-Cid L, Roessner PM, Chapaprieta V, Öztürk S, Roider T, Bordas M, Izcue A, Colomer D, Dietrich S, Stilgenbauer S, Hanna B, Martín-Subero JI, Seiffert M. Llaó-Cid L, et al. Among authors: bordas m. Leukemia. 2021 Nov;35(11):3152-3162. doi: 10.1038/s41375-021-01198-1. Epub 2021 Mar 17. Leukemia. 2021. PMID: 33731848 Free PMC article.
EOMES and IL-10 regulate antitumor activity of T regulatory type 1 CD4+ T cells in chronic lymphocytic leukemia.
Roessner PM, Llaó Cid L, Lupar E, Roider T, Bordas M, Schifflers C, Arseni L, Gaupel AC, Kilpert F, Krötschel M, Arnold SJ, Sellner L, Colomer D, Stilgenbauer S, Dietrich S, Lichter P, Izcue A, Seiffert M. Roessner PM, et al. Among authors: bordas m. Leukemia. 2021 Aug;35(8):2311-2324. doi: 10.1038/s41375-021-01136-1. Epub 2021 Feb 1. Leukemia. 2021. PMID: 33526861 Free PMC article.
Discovery of EST73502, a Dual μ-Opioid Receptor Agonist and σ1 Receptor Antagonist Clinical Candidate for the Treatment of Pain.
García M, Virgili M, Alonso M, Alegret C, Farran J, Fernández B, Bordas M, Pascual R, Burgueño J, Vidal-Torres A, Fernández de Henestrosa AR, Ayet E, Merlos M, Vela JM, Plata-Salamán CR, Almansa C. García M, et al. Among authors: bordas m. J Med Chem. 2020 Dec 24;63(24):15508-15526. doi: 10.1021/acs.jmedchem.0c01127. Epub 2020 Oct 16. J Med Chem. 2020. PMID: 33064947
45 results