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Cerebrospinal fluid influx drives acute ischemic tissue swelling.
Science. 2020 Mar 13;367(6483):eaax7171. doi: 10.1126/science.aax7171. Epub 2020 Jan 30.
Science. 2020.
PMID: 32001524
Free PMC article.
Cerebrospinal fluid is a significant fluid source for anoxic cerebral oedema.
Du T, Mestre H, Kress BT, Liu G, Sweeney AM, Samson AJ, Rasmussen MK, Mortensen KN, Bork PAR, Peng W, Olveda GE, Bashford L, Toro ER, Tithof J, Kelley DH, Thomas JH, Hjorth PG, Martens EA, Mehta RI, Hirase H, Mori Y, Nedergaard M.
Du T, et al. Among authors: bork par.
Brain. 2022 Apr 18;145(2):787-797. doi: 10.1093/brain/awab293.
Brain. 2022.
PMID: 34581781
Free PMC article.
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A network model of glymphatic flow under different experimentally-motivated parametric scenarios.
Tithof J, Boster KAS, Bork PAR, Nedergaard M, Thomas JH, Kelley DH.
Tithof J, et al. Among authors: bork par.
iScience. 2022 Apr 14;25(5):104258. doi: 10.1016/j.isci.2022.104258. eCollection 2022 May 20.
iScience. 2022.
PMID: 35521514
Free PMC article.
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A real-time in vivo clearance assay for quantification of glymphatic efflux.
Plá V, Bork P, Harnpramukkul A, Olveda G, Ladrón-de-Guevara A, Giannetto MJ, Hussain R, Wang W, Kelley DH, Hablitz LM, Nedergaard M.
Plá V, et al.
Cell Rep. 2022 Sep 13;40(11):111320. doi: 10.1016/j.celrep.2022.111320.
Cell Rep. 2022.
PMID: 36103828
Free article.
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Delivery of gene therapy through a cerebrospinal fluid conduit to rescue hearing in adult mice.
Mathiesen BK, Miyakoshi LM, Cederroth CR, Tserga E, Versteegh C, Bork PAR, Hauglund NL, Gomolka RS, Mori Y, Edvall NK, Rouse S, Møllgård K, Holt JR, Nedergaard M, Canlon B.
Mathiesen BK, et al. Among authors: bork par.
Sci Transl Med. 2023 Jun 28;15(702):eabq3916. doi: 10.1126/scitranslmed.abq3916. Epub 2023 Jun 28.
Sci Transl Med. 2023.
PMID: 37379370
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Astrocyte endfeet may theoretically act as valves to convert pressure oscillations to glymphatic flow.
Bork PAR, Ladrón-de-Guevara A, Christensen AH, Jensen KH, Nedergaard M, Bohr T.
Bork PAR, et al.
J R Soc Interface. 2023 Jul;20(204):20230050. doi: 10.1098/rsif.2023.0050. Epub 2023 Jul 12.
J R Soc Interface. 2023.
PMID: 37434503
Free PMC article.
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Glymphatic fluid transport is suppressed by the aquaporin-4 inhibitor AER-271.
Giannetto MJ, Gomolka RS, Gahn-Martinez D, Newbold EJ, Bork PAR, Chang E, Gresser M, Thompson T, Mori Y, Nedergaard M.
Giannetto MJ, et al. Among authors: bork par.
Glia. 2024 May;72(5):982-998. doi: 10.1002/glia.24515. Epub 2024 Feb 16.
Glia. 2024.
PMID: 38363040
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Modeling of brain efflux: Constraints of brain surfaces.
Bork PAR, Hauglund NL, Mori Y, Møllgård K, Hjorth PG, Nedergaard M.
Bork PAR, et al.
Proc Natl Acad Sci U S A. 2024 Apr 16;121(16):e2318444121. doi: 10.1073/pnas.2318444121. Epub 2024 Apr 10.
Proc Natl Acad Sci U S A. 2024.
PMID: 38598340
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