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Page 1
R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5.
Ruffner H, Sprunger J, Charlat O, Leighton-Davies J, Grosshans B, Salathe A, Zietzling S, Beck V, Therier M, Isken A, Xie Y, Zhang Y, Hao H, Shi X, Liu D, Song Q, Clay I, Hintzen G, Tchorz J, Bouchez LC, Michaud G, Finan P, Myer VE, Bouwmeester T, Porter J, Hild M, Bassilana F, Parker CN, Cong F. Ruffner H, et al. Among authors: bouchez lc. PLoS One. 2012;7(7):e40976. doi: 10.1371/journal.pone.0040976. Epub 2012 Jul 16. PLoS One. 2012. PMID: 22815884 Free PMC article.
Screening of Intestinal Crypt Organoids: A Simple Readout for Complex Biology.
Ley S, Galuba O, Salathe A, Melin N, Aebi A, Pikiolek M, Knehr J, Carbone W, Beibel M, Nigsch F, Roma G, d'Ario G, Kirkland S, Bouchez LC, Gubser Keller C, Bouwmeester T, Parker CN, Ruffner H. Ley S, et al. Among authors: bouchez lc. SLAS Discov. 2017 Jun;22(5):571-582. doi: 10.1177/2472555216683651. Epub 2017 Jan 6. SLAS Discov. 2017. PMID: 28345372 Free article.
BET bromodomain inhibitors regulate keratinocyte plasticity.
Schutzius G, Kolter C, Bergling S, Tortelli F, Fuchs F, Renner S, Guagnano V, Cotesta S, Rueeger H, Faller M, Bouchez L, Salathe A, Nigsch F, Richards SM, Louis M, Gruber V, Aebi A, Turner J, Grandjean F, Li J, Dimitri C, Thomas JR, Schirle M, Blank J, Drueckes P, Vaupel A, Tiedt R, Manley PW, Klopp J, Hemmig R, Zink F, Leroy N, Carbone W, Roma G, Keller CG, Dales N, Beyerbach A, Zimmerlin A, Bonenfant D, Terranova R, Berwick A, Sahambi S, Reynolds A, Jennings LL, Ruffner H, Tarsa P, Bouwmeester T, Driver V, Frederiksen M, Lohmann F, Kirkland S. Schutzius G, et al. Nat Chem Biol. 2021 Mar;17(3):280-290. doi: 10.1038/s41589-020-00716-z. Epub 2021 Jan 18. Nat Chem Biol. 2021. PMID: 33462494
Identification of Small Molecules Which Induce Skeletal Muscle Differentiation in Embryonic Stem Cells via Activation of the Wnt and Inhibition of Smad2/3 and Sonic Hedgehog Pathways.
Lee H, Haller C, Manneville C, Doll T, Fruh I, Keller CG, Richards SM, Ibig-Rehm Y, Patoor M, Goette M, Bouchez LC, Mueller M. Lee H, et al. Among authors: bouchez lc. Stem Cells. 2016 Feb;34(2):299-310. doi: 10.1002/stem.2228. Epub 2015 Nov 17. Stem Cells. 2016. PMID: 26577380
Hypoxia-Activated, Small-Molecule-Induced Gene Expression.
Collins SL, Saha J, Bouchez LC, Hammond EM, Conway SJ. Collins SL, et al. Among authors: bouchez lc. ACS Chem Biol. 2018 Dec 21;13(12):3354-3360. doi: 10.1021/acschembio.8b00858. Epub 2018 Dec 7. ACS Chem Biol. 2018. PMID: 30451487
CXCR4 as biomarker for radioresistant cancer stem cells.
Trautmann F, Cojoc M, Kurth I, Melin N, Bouchez LC, Dubrovska A, Peitzsch C. Trautmann F, et al. Among authors: bouchez lc. Int J Radiat Biol. 2014 Aug;90(8):687-99. doi: 10.3109/09553002.2014.906766. Int J Radiat Biol. 2014. PMID: 24650104
Pan-Src family kinase inhibitors replace Sox2 during the direct reprogramming of somatic cells.
Staerk J, Lyssiotis CA, Medeiro LA, Bollong M, Foreman RK, Zhu S, Garcia M, Gao Q, Bouchez LC, Lairson LL, Charette BD, Supekova L, Janes J, Brinker A, Cho CY, Jaenisch R, Schultz PG. Staerk J, et al. Among authors: bouchez lc. Angew Chem Int Ed Engl. 2011 Jun 14;50(25):5734-6. doi: 10.1002/anie.201101042. Epub 2011 May 5. Angew Chem Int Ed Engl. 2011. PMID: 21547985 Free PMC article. No abstract available.
A stem cell-based approach to cartilage repair.
Johnson K, Zhu S, Tremblay MS, Payette JN, Wang J, Bouchez LC, Meeusen S, Althage A, Cho CY, Wu X, Schultz PG. Johnson K, et al. Among authors: bouchez lc. Science. 2012 May 11;336(6082):717-21. doi: 10.1126/science.1215157. Epub 2012 Apr 5. Science. 2012. PMID: 22491093
21 results