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Limited heterogeneity of known driver gene mutations among the metastases of individual patients with pancreatic cancer.
Makohon-Moore AP, Zhang M, Reiter JG, Bozic I, Allen B, Kundu D, Chatterjee K, Wong F, Jiao Y, Kohutek ZA, Hong J, Attiyeh M, Javier B, Wood LD, Hruban RH, Nowak MA, Papadopoulos N, Kinzler KW, Vogelstein B, Iacobuzio-Donahue CA. Makohon-Moore AP, et al. Among authors: bozic i. Nat Genet. 2017 Mar;49(3):358-366. doi: 10.1038/ng.3764. Epub 2017 Jan 16. Nat Genet. 2017. PMID: 28092682 Free PMC article.
Accumulation of driver and passenger mutations during tumor progression.
Bozic I, Antal T, Ohtsuki H, Carter H, Kim D, Chen S, Karchin R, Kinzler KW, Vogelstein B, Nowak MA. Bozic I, et al. Proc Natl Acad Sci U S A. 2010 Oct 26;107(43):18545-50. doi: 10.1073/pnas.1010978107. Epub 2010 Sep 27. Proc Natl Acad Sci U S A. 2010. PMID: 20876136 Free PMC article.
Distant metastasis occurs late during the genetic evolution of pancreatic cancer.
Yachida S, Jones S, Bozic I, Antal T, Leary R, Fu B, Kamiyama M, Hruban RH, Eshleman JR, Nowak MA, Velculescu VE, Kinzler KW, Vogelstein B, Iacobuzio-Donahue CA. Yachida S, et al. Among authors: bozic i. Nature. 2010 Oct 28;467(7319):1114-7. doi: 10.1038/nature09515. Nature. 2010. PMID: 20981102 Free PMC article.
Dynamics of targeted cancer therapy.
Bozic I, Allen B, Nowak MA. Bozic I, et al. Trends Mol Med. 2012 Jun;18(6):311-6. doi: 10.1016/j.molmed.2012.04.006. Epub 2012 May 15. Trends Mol Med. 2012. PMID: 22595628 Free PMC article.
Evolutionary dynamics of cancer in response to targeted combination therapy.
Bozic I, Reiter JG, Allen B, Antal T, Chatterjee K, Shah P, Moon YS, Yaqubie A, Kelly N, Le DT, Lipson EJ, Chapman PB, Diaz LA Jr, Vogelstein B, Nowak MA. Bozic I, et al. Elife. 2013 Jun 25;2:e00747. doi: 10.7554/eLife.00747. Elife. 2013. PMID: 23805382 Free PMC article.
Cancer. Unwanted evolution.
Bozic I, Nowak MA. Bozic I, et al. Science. 2013 Nov 22;342(6161):938-9. doi: 10.1126/science.1247887. Science. 2013. PMID: 24264980 No abstract available.
166 results