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Page 1
BPIFA2 as a Novel Early Biomarker to Identify Fatal Radiation Injury After Radiation Exposure.
He L, Zhou S, Li W, Wang Q, Qi Z, Zhou P, Wang Z, Chen J, Li Y, Lin Z. He L, et al. Dose Response. 2022 Apr 11;20(1):15593258221086478. doi: 10.1177/15593258221086478. eCollection 2022 Jan-Mar. Dose Response. 2022. PMID: 35431693 Free PMC article.
METHODS: A rabbit anti-mouse BPIFA2 polyclonal antibody was prepared to detect the expression of BPIFA2. ...RESULTS: BPIFA2 in mice serum were significantly increased at 1-12 h post-irradiation at .5-10 Gy, and increased again significantly at 3 d after 10 Gy …
METHODS: A rabbit anti-mouse BPIFA2 polyclonal antibody was prepared to detect the expression of BPIFA2. ...RESULTS: BPIFA2 …
The parotid secretory protein BPIFA2 is a salivary surfactant that affects lipopolysaccharide action.
Nandula SR, Huxford I, Wheeler TT, Aparicio C, Gorr SU. Nandula SR, et al. Exp Physiol. 2020 Aug;105(8):1280-1292. doi: 10.1113/EP088567. Epub 2020 Jun 19. Exp Physiol. 2020. PMID: 32390232 Free PMC article.
These results suggest that the lipopolysaccharide-binding activity of BPIFA2 affects the activity of ingested lipopolysaccharide in the intestine and that BPIFA2 depletion causes mild metabolic endotoxaemia. ...To address this question, Bpifa2 knockout (Bp …
These results suggest that the lipopolysaccharide-binding activity of BPIFA2 affects the activity of ingested lipopolysaccharide in t …
Isolation, biochemical characterization and anti-bacterial activity of BPIFA2 protein.
Prokopovic V, Popovic M, Andjelkovic U, Marsavelski A, Raskovic B, Gavrovic-Jankulovic M, Polovic N. Prokopovic V, et al. Arch Oral Biol. 2014 Mar;59(3):302-9. doi: 10.1016/j.archoralbio.2013.12.005. Epub 2013 Dec 22. Arch Oral Biol. 2014. PMID: 24581853
The isolated BPIFA2 was identified by trypsin mass fingerprinting and characterized by electrophoretic methods. ...In the time kill study, 32mug/mL BPIFA2 showed clear bactericidal activity and did not cause any aggregation of bacteria. ...
The isolated BPIFA2 was identified by trypsin mass fingerprinting and characterized by electrophoretic methods. ...In the time kill s …
Salivary BPIFA1 (SPLUNC1) and BPIFA2 (SPLUNC2 A) are modified by head and neck cancer radiotherapy.
González-Arriagada WA, Ramos LM, Silva AA, Vargas PA, Coletta RD, Bingle L, Lopes MA. González-Arriagada WA, et al. Oral Surg Oral Med Oral Pathol Oral Radiol. 2015 Jan;119(1):48-58. doi: 10.1016/j.oooo.2014.09.026. Epub 2014 Sep 30. Oral Surg Oral Med Oral Pathol Oral Radiol. 2015. PMID: 25482547
Salivary BPIFA1 expression levels were similar between the control group and the patient group before treatment. On the other hand, BPIFA2 levels were higher in the patient group before treatment compared with the control group. BPIFA concentration was modified by radiothe …
Salivary BPIFA1 expression levels were similar between the control group and the patient group before treatment. On the other hand, BPIFA …
Salivary BPIFA proteins are altered in patients undergoing hematopoietic cell transplantation.
Innocentini LMAR, Silva AA, Carvalho MA, Coletta RD, Corrêa MEP, Bingle L, Bingle CD, Vargas PA, Lopes MA. Innocentini LMAR, et al. Oral Dis. 2022 May;28(4):1279-1288. doi: 10.1111/odi.13832. Epub 2021 Apr 5. Oral Dis. 2022. PMID: 33682222 Free article.
RESULTS: Auto-HCT patients showed increased levels of BPIFA1 (p = .021) and BPIFA2 at D+7 (p = .040), whereas allo-HCT group demonstrated decreased expression of BPIFA2 at D+8 (p = .002) and at D+80 (p = .001) and a significant association between BPIFA2 low …
RESULTS: Auto-HCT patients showed increased levels of BPIFA1 (p = .021) and BPIFA2 at D+7 (p = .040), whereas allo-HCT group demonstr …
Renal progenitor cells revert LPS-induced endothelial-to-mesenchymal transition by secreting CXCL6, SAA4, and BPIFA2 antiseptic peptides.
Sallustio F, Stasi A, Curci C, Divella C, Picerno A, Franzin R, De Palma G, Rutigliano M, Lucarelli G, Battaglia M, Staffieri F, Crovace A, Pertosa GB, Castellano G, Gallone A, Gesualdo L. Sallustio F, et al. FASEB J. 2019 Oct;33(10):10753-10766. doi: 10.1096/fj.201900351R. Epub 2019 Jul 3. FASEB J. 2019. PMID: 31268775
Finally, in a swine model of LPS-induced AKI, we observed that activated ARPCs secreted CXCL6, SAA4, and BPIFA2 as a defense response. These data open new perspectives on the treatment of both sepsis- and endotoxemia-induced AKI, suggesting an underestimated role of ARPCs …
Finally, in a swine model of LPS-induced AKI, we observed that activated ARPCs secreted CXCL6, SAA4, and BPIFA2 as a defense response …
BPI Fold-Containing Family A Member 2/Parotid Secretory Protein Is an Early Biomarker of AKI.
Kota SK, Pernicone E, Leaf DE, Stillman IE, Waikar SS, Kota SB. Kota SK, et al. J Am Soc Nephrol. 2017 Dec;28(12):3473-3478. doi: 10.1681/ASN.2016121265. Epub 2017 Aug 3. J Am Soc Nephrol. 2017. PMID: 28775000 Free PMC article.
In our study, AKI induced Bpifa2 expression in the kidneys of mice within 3 hours. Furthermore, we detected BPIFA2 protein in plasma and urine in these models as early as 6 hours after injury. ...Notably, patients with AKI had higher blood and urine levels of BPI …
In our study, AKI induced Bpifa2 expression in the kidneys of mice within 3 hours. Furthermore, we detected BPIFA2 protein in …
RNA-Seq Analysis of UPM-Exposed Epithelium Co-Cultivated with Macrophages and Dendritic Cells in Obstructive Lung Diseases.
Misiukiewicz-Stępien P, Mierzejewski M, Zajusz-Zubek E, Goryca K, Adamska D, Szeląg M, Krenke R, Paplińska-Goryca M. Misiukiewicz-Stępien P, et al. Int J Mol Sci. 2022 Aug 15;23(16):9125. doi: 10.3390/ijms23169125. Int J Mol Sci. 2022. PMID: 36012391 Free PMC article.
RNA-Seq analysis found differences in seven (CYP1B1, CYP1B1-AS1, NCF1, ME1, LINC02029, BPIFA2, EEF1A2), five (CYP1B1, ARC, ENPEP, RASD1, CYP1B1-AS1), and six (CYP1B1, CYP1B1-AS1, IRF4, ATP1B2, TIPARP, CCL22) differentially expressed genes between UPM exposed and unexposed …
RNA-Seq analysis found differences in seven (CYP1B1, CYP1B1-AS1, NCF1, ME1, LINC02029, BPIFA2, EEF1A2), five (CYP1B1, ARC, ENPEP, RAS …
Novel acute kidney injury biomarkers: their characteristics, utility and concerns.
Beker BM, Corleto MG, Fieiras C, Musso CG. Beker BM, et al. Int Urol Nephrol. 2018 Apr;50(4):705-713. doi: 10.1007/s11255-017-1781-x. Epub 2018 Jan 6. Int Urol Nephrol. 2018. PMID: 29307055 Review.
Among the main AKI biomarkers the neutrophil gelatinase-associated lipocalin, cystatin C, kidney injury molecule-1, monocyte chemotactic peptide-1, N-acetyl-beta-D-glucosaminidase, interleukin-18, liver-type fatty acid-binding protein, netrin-1, cycle arrest markers, endogenous o …
Among the main AKI biomarkers the neutrophil gelatinase-associated lipocalin, cystatin C, kidney injury molecule-1, monocyte chemotactic pep …
95 results