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7-Chloro-5-(furan-3-yl)-3-methyl-4H-benzo[e][1,2,4]thiadiazine 1,1-Dioxide as Positive Allosteric Modulator of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor. The End of the Unsaturated-Inactive Paradigm?
Citti C, Battisti UM, Cannazza G, Jozwiak K, Stasiak N, Puja G, Ravazzini F, Ciccarella G, Braghiroli D, Parenti C, Troisi L, Zoli M. Citti C, et al. Among authors: braghiroli d. ACS Chem Neurosci. 2016 Feb 17;7(2):149-60. doi: 10.1021/acschemneuro.5b00257. Epub 2015 Dec 2. ACS Chem Neurosci. 2016. PMID: 26580317
Molecular modeling studies, synthesis, configurational stability and biological activity of 8-chloro-2,3,5,6-tetrahydro-3,6-dimethyl-pyrrolo[1,2,3-de]-1,2,4-benzothiadiazine 1,1-dioxide.
Battisti UM, Carrozzo MM, Cannazza G, Puia G, Troisi L, Braghiroli D, Parenti C, Jozwiak K. Battisti UM, et al. Among authors: braghiroli d. Bioorg Med Chem. 2011 Dec 1;19(23):7111-9. doi: 10.1016/j.bmc.2011.09.063. Epub 2011 Oct 5. Bioorg Med Chem. 2011. PMID: 22019464 Free article.
Design, stereoselective synthesis, configurational stability and biological activity of 7-chloro-9-(furan-3-yl)-2,3,3a,4-tetrahydro-1H-benzo[e]pyrrolo[2,1-c][1,2,4]thiadiazine 5,5-dioxide.
Carrozzo MM, Battisti UM, Cannazza G, Puia G, Ravazzini F, Falchicchio A, Perrone S, Citti C, Jozwiak K, Braghiroli D, Parenti C, Troisi L. Carrozzo MM, et al. Among authors: braghiroli d. Bioorg Med Chem. 2014 Sep 1;22(17):4667-76. doi: 10.1016/j.bmc.2014.07.017. Epub 2014 Jul 18. Bioorg Med Chem. 2014. PMID: 25126714 Free article.
A novel class of allosteric modulators of AMPA/Kainate receptors.
Cannazza G, Jozwiak K, Parenti C, Braghiroli D, Carrozzo MM, Puia G, Losi G, Baraldi M, Lindner W, Wainer IW. Cannazza G, et al. Among authors: braghiroli d. Bioorg Med Chem Lett. 2009 Feb 15;19(4):1254-7. doi: 10.1016/j.bmcl.2008.12.094. Epub 2008 Dec 30. Bioorg Med Chem Lett. 2009. PMID: 19162477 Free PMC article.
On-line racemization by high-performance liquid chromatography.
Cannazza G, Carrozzo MM, Battisti U, Braghiroli D, Parenti C. Cannazza G, et al. Among authors: braghiroli d. J Chromatogr A. 2009 Jul 24;1216(30):5655-9. doi: 10.1016/j.chroma.2009.05.057. Epub 2009 May 29. J Chromatogr A. 2009. PMID: 19539938
44 results