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Interfering with the Tumor-Immune Interface: Making Way for Triazine-Based Small Molecules as Novel PD-L1 Inhibitors.
Russomanno P, Assoni G, Amato J, D'Amore VM, Scaglia R, Brancaccio D, Pedrini M, Polcaro G, La Pietra V, Orlando P, Falzoni M, Cerofolini L, Giuntini S, Fragai M, Pagano B, Donati G, Novellino E, Quintavalle C, Condorelli G, Sabbatino F, Seneci P, Arosio D, Pepe S, Marinelli L. Russomanno P, et al. Among authors: brancaccio d. J Med Chem. 2021 Nov 11;64(21):16020-16045. doi: 10.1021/acs.jmedchem.1c01409. Epub 2021 Oct 20. J Med Chem. 2021. PMID: 34670084
Structure-based lead optimization and biological evaluation of BAX direct activators as novel potential anticancer agents.
Stornaiuolo M, La Regina G, Passacantilli S, Grassia G, Coluccia A, La Pietra V, Giustiniano M, Cassese H, Di Maro S, Brancaccio D, Taliani S, Ialenti A, Silvestri R, Martini C, Novellino E, Marinelli L. Stornaiuolo M, et al. Among authors: brancaccio d. J Med Chem. 2015 Mar 12;58(5):2135-48. doi: 10.1021/jm501123r. Epub 2015 Feb 25. J Med Chem. 2015. PMID: 25668341
Exploring the N-Terminal Region of C-X-C Motif Chemokine 12 (CXCL12): Identification of Plasma-Stable Cyclic Peptides As Novel, Potent C-X-C Chemokine Receptor Type 4 (CXCR4) Antagonists.
Di Maro S, Trotta AM, Brancaccio D, Di Leva FS, La Pietra V, Ieranò C, Napolitano M, Portella L, D'Alterio C, Siciliano RA, Sementa D, Tomassi S, Carotenuto A, Novellino E, Scala S, Marinelli L. Di Maro S, et al. Among authors: d alterio c, brancaccio d. J Med Chem. 2016 Sep 22;59(18):8369-80. doi: 10.1021/acs.jmedchem.6b00695. Epub 2016 Sep 9. J Med Chem. 2016. PMID: 27571038
Computer-Aided Identification and Lead Optimization of Dual Murine Double Minute 2 and 4 Binders: Structure-Activity Relationship Studies and Pharmacological Activity.
Giustiniano M, Daniele S, Pelliccia S, La Pietra V, Pietrobono D, Brancaccio D, Cosconati S, Messere A, Giuntini S, Cerofolini L, Fragai M, Luchinat C, Taliani S, La Regina G, Da Settimo F, Silvestri R, Martini C, Novellino E, Marinelli L. Giustiniano M, et al. Among authors: brancaccio d. J Med Chem. 2017 Oct 12;60(19):8115-8130. doi: 10.1021/acs.jmedchem.7b00912. Epub 2017 Sep 30. J Med Chem. 2017. PMID: 28921985
Simultaneous Targeting of RGD-Integrins and Dual Murine Double Minute Proteins in Glioblastoma Multiforme.
Merlino F, Daniele S, La Pietra V, Di Maro S, Di Leva FS, Brancaccio D, Tomassi S, Giuntini S, Cerofolini L, Fragai M, Luchinat C, Reichart F, Cavallini C, Costa B, Piccarducci R, Taliani S, Da Settimo F, Martini C, Kessler H, Novellino E, Marinelli L. Merlino F, et al. Among authors: brancaccio d. J Med Chem. 2018 Jun 14;61(11):4791-4809. doi: 10.1021/acs.jmedchem.8b00004. Epub 2018 Jun 4. J Med Chem. 2018. PMID: 29775303
Structure-Activity Relationships and Biological Characterization of a Novel, Potent, and Serum Stable C-X-C Chemokine Receptor Type 4 (CXCR4) Antagonist.
Di Maro S, Di Leva FS, Trotta AM, Brancaccio D, Portella L, Aurilio M, Tomassi S, Messere A, Sementa D, Lastoria S, Carotenuto A, Novellino E, Scala S, Marinelli L. Di Maro S, et al. Among authors: brancaccio d. J Med Chem. 2017 Dec 14;60(23):9641-9652. doi: 10.1021/acs.jmedchem.7b01062. Epub 2017 Nov 20. J Med Chem. 2017. PMID: 29125295
279 results