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Vinblastine-induced phosphorylation of Bcl-2 and Bcl-XL is mediated by JNK and occurs in parallel with inactivation of the Raf-1/MEK/ERK cascade.
J Biol Chem. 2000 Sep 29;275(39):29980-5. doi: 10.1074/jbc.M003776200.
J Biol Chem. 2000.
PMID: 10913135
Free article.
The JNK, ERK and p53 pathways play distinct roles in apoptosis mediated by the antitumor agents vinblastine, doxorubicin, and etoposide.
Brantley-Finley C, Lyle CS, Du L, Goodwin ME, Hall T, Szwedo D, Kaushal GP, Chambers TC.
Brantley-Finley C, et al.
Biochem Pharmacol. 2003 Aug 1;66(3):459-69. doi: 10.1016/s0006-2952(03)00255-7.
Biochem Pharmacol. 2003.
PMID: 12907245
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