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In Vitro Potency and Preclinical Pharmacokinetic Comparison of All-D-Enantiomeric Peptides Developed for the Treatment of Alzheimer's Disease.
Schartmann E, Schemmert S, Niemietz N, Honold D, Ziehm T, Tusche M, Elfgen A, Gering I, Brener O, Shah NJ, Langen KJ, Kutzsche J, Willbold D, Willuweit A. Schartmann E, et al. Among authors: brener o. J Alzheimers Dis. 2018;64(3):859-873. doi: 10.3233/JAD-180165. J Alzheimers Dis. 2018. PMID: 29966196 Free PMC article.
Optimization of the All-D Peptide D3 for Aβ Oligomer Elimination.
Klein AN, Ziehm T, Tusche M, Buitenhuis J, Bartnik D, Boeddrich A, Wiglenda T, Wanker E, Funke SA, Brener O, Gremer L, Kutzsche J, Willbold D. Klein AN, et al. Among authors: brener o. PLoS One. 2016 Apr 22;11(4):e0153035. doi: 10.1371/journal.pone.0153035. eCollection 2016. PLoS One. 2016. PMID: 27105346 Free PMC article.
QIAD assay for quantitating a compound's efficacy in elimination of toxic Aβ oligomers.
Brener O, Dunkelmann T, Gremer L, van Groen T, Mirecka EA, Kadish I, Willuweit A, Kutzsche J, Jürgens D, Rudolph S, Tusche M, Bongen P, Pietruszka J, Oesterhelt F, Langen KJ, Demuth HU, Janssen A, Hoyer W, Funke SA, Nagel-Steger L, Willbold D. Brener O, et al. Sci Rep. 2015 Sep 23;5:13222. doi: 10.1038/srep13222. Sci Rep. 2015. PMID: 26394756 Free PMC article.
21 results