Breusegem SY - Search Results

1

Genome-wide RNAi screen reveals a role for multipass membrane proteins in endosome-to-golgi retrieval.

Breusegem SY, Seaman MNJ. Breusegem SY, et al. Cell Rep. 2014 Dec 11;9(5):1931-1945. doi: 10.1016/j.celrep.2014.10.053. Epub 2014 Nov 20. Cell Rep. 2014. PMID: 25464851 Free PMC article.

2

Recruitment of the endosomal WASH complex is mediated by the extended 'tail' of Fam21 binding to the retromer protein Vps35.

Harbour ME, Breusegem SY, Seaman MN. Harbour ME, et al. Among authors: breusegem sy. Biochem J. 2012 Feb 15;442(1):209-20. doi: 10.1042/BJ20111761. Biochem J. 2012. PMID: 22070227

3

Image-based and biochemical assays to investigate endosomal protein sorting.

Breusegem SY, Seaman MN. Breusegem SY, et al. Methods Enzymol. 2014;534:155-78. doi: 10.1016/B978-0-12-397926-1.00009-3. Methods Enzymol. 2014. PMID: 24359953

4

Mutation in VPS35 associated with Parkinson's disease impairs WASH complex association and inhibits autophagy.

Zavodszky E, Seaman MN, Moreau K, Jimenez-Sanchez M, Breusegem SY, Harbour ME, Rubinsztein DC. Zavodszky E, et al. Among authors: breusegem sy. Nat Commun. 2014 May 13;5:3828. doi: 10.1038/ncomms4828. Nat Commun. 2014. PMID: 24819384 Free PMC article.

5

Analysis of novel endosome-to-Golgi retrieval genes reveals a role for PLD3 in regulating endosomal protein sorting and amyloid precursor protein processing.

Mukadam AS, Breusegem SY, Seaman MNJ. Mukadam AS, et al. Among authors: breusegem sy. Cell Mol Life Sci. 2018 Jul;75(14):2613-2625. doi: 10.1007/s00018-018-2752-9. Epub 2018 Jan 24. Cell Mol Life Sci. 2018. PMID: 29368044 Free PMC article.

6

Inhibition of TBC1D5 activates Rab7a and can enhance the function of the retromer cargo-selective complex.

Seaman MNJ, Mukadam AS, Breusegem SY. Seaman MNJ, et al. Among authors: breusegem sy. J Cell Sci. 2018 Jun 21;131(12):jcs217398. doi: 10.1242/jcs.217398. J Cell Sci. 2018. PMID: 29777037 Free PMC article.

7

The cargo-selective retromer complex is a recruiting hub for protein complexes that regulate endosomal tubule dynamics.

Harbour ME, Breusegem SY, Antrobus R, Freeman C, Reid E, Seaman MN. Harbour ME, et al. Among authors: breusegem sy. J Cell Sci. 2010 Nov 1;123(Pt 21):3703-17. doi: 10.1242/jcs.071472. Epub 2010 Oct 5. J Cell Sci. 2010. PMID: 20923837 Free PMC article.

8

De novo deleterious genetic variations target a biological network centered on Aβ peptide in early-onset Alzheimer disease.

Rovelet-Lecrux A, Charbonnier C, Wallon D, Nicolas G, Seaman MN, Pottier C, Breusegem SY, Mathur PP, Jenardhanan P, Le Guennec K, Mukadam AS, Quenez O, Coutant S, Rousseau S, Richard AC, Boland A, Deleuze JF, Frebourg T, Hannequin D, Campion D; CNR-MAJ collaborators. Rovelet-Lecrux A, et al. Among authors: breusegem sy. Mol Psychiatry. 2015 Sep;20(9):1046-56. doi: 10.1038/mp.2015.100. Epub 2015 Jul 21. Mol Psychiatry. 2015. PMID: 26194182

9

Differential regulation of the renal sodium-phosphate cotransporters NaPi-IIa, NaPi-IIc, and PiT-2 in dietary potassium deficiency.

Breusegem SY, Takahashi H, Giral-Arnal H, Wang X, Jiang T, Verlander JW, Wilson P, Miyazaki-Anzai S, Sutherland E, Caldas Y, Blaine JT, Segawa H, Miyamoto K, Barry NP, Levi M. Breusegem SY, et al. Am J Physiol Renal Physiol. 2009 Aug;297(2):F350-61. doi: 10.1152/ajprenal.90765.2008. Epub 2009 Jun 3. Am J Physiol Renal Physiol. 2009. PMID: 19493963 Free PMC article.

Kidney Int 60: 694-704, 2001; Inoue M, Digman MA, Cheng M, Breusegem SY, Halaihel N, Sorribas V, Mantulin WW, Gratton E, Barry NP, Levi M. ...

Kidney Int 60: 694-704, 2001; Inoue M, Digman MA, Cheng M, Breusegem SY, Halaihel N, Sorribas V, Mantulin WW, Gratton E, Barry …

10

Inhibition of the acetyltransferase NAT10 normalizes progeric and aging cells by rebalancing the Transportin-1 nuclear import pathway.

Larrieu D, Viré E, Robson S, Breusegem SY, Kouzarides T, Jackson SP. Larrieu D, et al. Among authors: breusegem sy. Sci Signal. 2018 Jul 3;11(537):eaar5401. doi: 10.1126/scisignal.aar5401. Sci Signal. 2018. PMID: 29970603 Free PMC article.

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