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The pleiotropic effects of α-thalassemia on HbSS and HbSC sickle cell disease: Reduced erythrocyte cation co-transport activity, serum erythropoietin, and transfusion burden, do not translate into increased survival.
Brewin JN, Nardo-Marino A, Stuart-Smith S, El Hoss S, Hanneman A, Strouboulis J, Menzel S, Gibson JS, Rees DC. Brewin JN, et al. Am J Hematol. 2022 Oct;97(10):1275-1285. doi: 10.1002/ajh.26652. Epub 2022 Jul 18. Am J Hematol. 2022. PMID: 35802781 Free PMC article.
The super sickling haemoglobin HbS-Oman: a study of red cell sickling, K+ permeability and associations with disease severity in patients heterozygous for HbA and HbS-Oman (HbA/S-Oman genotype).
Al Balushi HWM, Wali Y, Al Awadi M, Al-Subhi T, Rees DC, Brewin JN, Hannemann A, Gibson JS. Al Balushi HWM, et al. Among authors: brewin jn. Br J Haematol. 2017 Oct;179(2):256-265. doi: 10.1111/bjh.14851. Epub 2017 Jul 12. Br J Haematol. 2017. PMID: 28699687 Free article. Clinical Trial.
A gain of function variant in PIEZO1 (E756del) and sickle cell disease.
Rooks H, Brewin J, Gardner K, Chakravorty S, Menzel S, Hannemann A, Gibson J, Rees DC. Rooks H, et al. Haematologica. 2019 Mar;104(3):e91-e93. doi: 10.3324/haematol.2018.202697. Epub 2018 Sep 20. Haematologica. 2019. PMID: 30237267 Free PMC article. No abstract available.
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