Brinton RD - Search Results

1

Data-driven identification of endophenotypes of Alzheimer's disease progression: implications for clinical trials and therapeutic interventions.

Geifman N, Kennedy RE, Schneider LS, Buchan I, Brinton RD. Geifman N, et al. Among authors: brinton rd. Alzheimers Res Ther. 2018 Jan 15;10(1):4. doi: 10.1186/s13195-017-0332-0. Alzheimers Res Ther. 2018. PMID: 29370871 Free PMC article. Clinical Trial.

2

Therapeutic potential of neurogenesis for prevention and recovery from Alzheimer's disease: allopregnanolone as a proof of concept neurogenic agent.

Brinton RD, Wang JM. Brinton RD, et al. Curr Alzheimer Res. 2006 Jul;3(3):185-90. doi: 10.2174/156720506777632817. Curr Alzheimer Res. 2006. PMID: 16842093 Review.

3

Estrogen receptor β-selective phytoestrogenic formulation prevents physical and neurological changes in a preclinical model of human menopause.

Zhao L, Mao Z, Schneider LS, Brinton RD. Zhao L, et al. Among authors: brinton rd. Menopause. 2011 Oct;18(10):1131-42. doi: 10.1097/gme.0b013e3182175b66. Menopause. 2011. PMID: 21738079 Free PMC article.

4

Shift in brain metabolism in late onset Alzheimer's disease: implications for biomarkers and therapeutic interventions.

Yao J, Rettberg JR, Klosinski LP, Cadenas E, Brinton RD. Yao J, et al. Among authors: brinton rd. Mol Aspects Med. 2011 Aug;32(4-6):247-57. doi: 10.1016/j.mam.2011.10.005. Epub 2011 Oct 21. Mol Aspects Med. 2011. PMID: 22024249 Free PMC article. Review.

5

Early intervention with an estrogen receptor β-selective phytoestrogenic formulation prolongs survival, improves spatial recognition memory, and slows progression of amyloid pathology in a female mouse model of Alzheimer's disease.

Zhao L, Mao Z, Chen S, Schneider LS, Brinton RD. Zhao L, et al. Among authors: brinton rd. J Alzheimers Dis. 2013;37(2):403-19. doi: 10.3233/JAD-122341. J Alzheimers Dis. 2013. PMID: 23948892 Free PMC article.

6

Evidence for benefit of statins to modify cognitive decline and risk in Alzheimer's disease.

Geifman N, Brinton RD, Kennedy RE, Schneider LS, Butte AJ. Geifman N, et al. Among authors: brinton rd. Alzheimers Res Ther. 2017 Feb 17;9(1):10. doi: 10.1186/s13195-017-0237-y. Alzheimers Res Ther. 2017. PMID: 28212683 Free PMC article.

7

Pharmacokinetics and safety profile of single-dose administration of an estrogen receptor β-selective phytoestrogenic (phytoSERM) formulation in perimenopausal and postmenopausal women.

Hernandez G, Zhao L, Franke AA, Chen YL, Mack WJ, Brinton RD, Schneider LS. Hernandez G, et al. Among authors: brinton rd. Menopause. 2018 Feb;25(2):191-196. doi: 10.1097/GME.0000000000000984. Menopause. 2018. PMID: 28926513 Free PMC article.

8

Safety and feasibility of estrogen receptor-β targeted phytoSERM formulation for menopausal symptoms: phase 1b/2a randomized clinical trial.

Schneider LS, Hernandez G, Zhao L, Franke AA, Chen YL, Pawluczyk S, Mack WJ, Brinton RD. Schneider LS, et al. Among authors: brinton rd. Menopause. 2019 Aug;26(8):874-884. doi: 10.1097/GME.0000000000001325. Menopause. 2019. PMID: 30889096 Free PMC article. Clinical Trial.

9

Retrospective analysis of phytoSERM for management of menopause-associated vasomotor symptoms and cognitive decline: a pilot study on pharmacogenomic effects of mitochondrial haplogroup and APOE genotype on therapeutic efficacy.

Wang Y, Hernandez G, Mack WJ, Schneider LS, Yin F, Brinton RD. Wang Y, et al. Among authors: brinton rd. Menopause. 2020 Jan;27(1):57-65. doi: 10.1097/GME.0000000000001418. Menopause. 2020. PMID: 31567873 Free PMC article. Clinical Trial.

10

Drug therapies for chronic conditions and risk of Alzheimer's disease and related dementias: A scoping review.

Thunell J, Chen Y, Joyce G, Barthold D, Shekelle PG, Brinton RD, Zissimopoulos J. Thunell J, et al. Among authors: brinton rd. Alzheimers Dement. 2021 Jan;17(1):41-48. doi: 10.1002/alz.12175. Epub 2020 Oct 8. Alzheimers Dement. 2021. PMID: 33090701 Free PMC article. Review.

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