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Comparative Genomics Provides Etiologic and Biological Insight into Melanoma Subtypes.
Newell F, Johansson PA, Wilmott JS, Nones K, Lakis V, Pritchard AL, Lo SN, Rawson RV, Kazakoff SH, Colebatch AJ, Koufariotis LT, Ferguson PM, Wood S, Leonard C, Law MH, Brooks KM, Broit N, Palmer JM, Couts KL, Vergara IA, Long GV, Barbour AP, Nieweg OE, Shivalingam B, Robinson WA, Stretch JR, Spillane AJ, Saw RPM, Shannon KF, Thompson JF, Mann GJ, Pearson JV, Scolyer RA, Waddell N, Hayward NK. Newell F, et al. Among authors: brooks km. Cancer Discov. 2022 Dec 2;12(12):2856-2879. doi: 10.1158/2159-8290.CD-22-0603. Cancer Discov. 2022. PMID: 36098958 Free PMC article.
Whole genome landscapes of uveal melanoma show an ultraviolet radiation signature in iris tumours.
Johansson PA, Brooks K, Newell F, Palmer JM, Wilmott JS, Pritchard AL, Broit N, Wood S, Carlino MS, Leonard C, Koufariotis LT, Nathan V, Beasley AB, Howlie M, Dawson R, Rizos H, Schmidt CW, Long GV, Hamilton H, Kiilgaard JF, Isaacs T, Gray ES, Rolfe OJ, Park JJ, Stark A, Mann GJ, Scolyer RA, Pearson JV, van Baren N, Waddell N, Wadt KW, McGrath LA, Warrier SK, Glasson W, Hayward NK. Johansson PA, et al. Nat Commun. 2020 May 15;11(1):2408. doi: 10.1038/s41467-020-16276-8. Nat Commun. 2020. PMID: 32415113 Free PMC article.
Loss-of-function variants in POT1 predispose to uveal melanoma.
Nathan V, Palmer JM, Johansson PA, Hamilton HR, Warrier SK, Glasson W, McGrath LA, Kahl VFS, Vasireddy RS, Pickett HA, Brooks KM, Pritchard AL, Hayward NK. Nathan V, et al. Among authors: brooks km. J Med Genet. 2021 Apr;58(4):234-236. doi: 10.1136/jmedgenet-2020-107098. Epub 2020 Sep 9. J Med Genet. 2021. PMID: 32907878 No abstract available.
Choroidal melanoma with synchronous Fuchs' adenoma and novel ATRX mutation.
Harford E, Palmer JM, Glasson WJ, Warrier SK, Whitehead KJ, Brooks KM, Johansson PA, Hayward NK, McGrath LA. Harford E, et al. Among authors: brooks km. Int J Retina Vitreous. 2022 Apr 1;8(1):24. doi: 10.1186/s40942-022-00374-4. Int J Retina Vitreous. 2022. PMID: 35365243 Free PMC article.
Tigilanol tiglate is an oncolytic small molecule that induces immunogenic cell death and enhances the response of both target and non-injected tumors to immune checkpoint blockade.
Cullen JK, Yap PY, Ferguson B, Bruce ZC, Koyama M, Handoko H, Hendrawan K, Simmons JL, Brooks KM, Johns J, Wilson ES, de Souza MMA, Broit N, Stewart P, Shelley D, McMahon T, Ogbourne SM, Nguyen TH, Lim YC, Pagani A, Appendino G, Gordon VA, Reddell PW, Boyle GM, Parsons PG. Cullen JK, et al. Among authors: brooks km. J Immunother Cancer. 2024 Apr 24;12(4):e006602. doi: 10.1136/jitc-2022-006602. J Immunother Cancer. 2024. PMID: 38658031 Free PMC article.
104 results