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Capitalizing on tumor genotyping: towards the design of mutation specific inhibitors of phosphoinsitide-3-kinase.
Adv Enzyme Regul. 2011;51(1):273-9. doi: 10.1016/j.advenzreg.2010.09.013. Epub 2010 Oct 28.
Adv Enzyme Regul. 2011.
PMID: 21035489
Free PMC article.
Review.
Structural basis of nSH2 regulation and lipid binding in PI3Kα.
Miller MS, Schmidt-Kittler O, Bolduc DM, Brower ET, Chaves-Moreira D, Allaire M, Kinzler KW, Jennings IG, Thompson PE, Cole PA, Amzel LM, Vogelstein B, Gabelli SB.
Miller MS, et al. Among authors: brower et.
Oncotarget. 2014 Jul 30;5(14):5198-208. doi: 10.18632/oncotarget.2263.
Oncotarget. 2014.
PMID: 25105564
Free PMC article.
Item in Clipboard
Activation of PI3Kα by physiological effectors and by oncogenic mutations: structural and dynamic effects.
Gabelli SB, Echeverria I, Alexander M, Duong-Ly KC, Chaves-Moreira D, Brower ET, Vogelstein B, Amzel LM.
Gabelli SB, et al. Among authors: brower et.
Biophys Rev. 2014 Mar 1;6(1):89-95. doi: 10.1007/s12551-013-0131-1.
Biophys Rev. 2014.
PMID: 25309634
Free PMC article.
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Naturally occurring variability in the envelope glycoprotein of HIV-1 and development of cell entry inhibitors.
Brower ET, Schön A, Freire E.
Brower ET, et al.
Biochemistry. 2010 Mar 23;49(11):2359-67. doi: 10.1021/bi1000933.
Biochemistry. 2010.
PMID: 20166763
Free PMC article.
Item in Clipboard
Inhibition of HIV-2 protease by HIV-1 protease inhibitors in clinical use.
Brower ET, Bacha UM, Kawasaki Y, Freire E.
Brower ET, et al.
Chem Biol Drug Des. 2008 Apr;71(4):298-305. doi: 10.1111/j.1747-0285.2008.00647.x. Epub 2008 Feb 28.
Chem Biol Drug Des. 2008.
PMID: 18312292
Item in Clipboard
Binding thermodynamics of the N-terminal peptide of the CCR5 coreceptor to HIV-1 envelope glycoprotein gp120.
Brower ET, Schön A, Klein JC, Freire E.
Brower ET, et al.
Biochemistry. 2009 Feb 3;48(4):779-85. doi: 10.1021/bi8021476.
Biochemistry. 2009.
PMID: 19170639
Free PMC article.
Item in Clipboard
Small-molecule CD4 mimics interact with a highly conserved pocket on HIV-1 gp120.
Madani N, Schön A, Princiotto AM, Lalonde JM, Courter JR, Soeta T, Ng D, Wang L, Brower ET, Xiang SH, Kwon YD, Huang CC, Wyatt R, Kwong PD, Freire E, Smith AB 3rd, Sodroski J.
Madani N, et al. Among authors: brower et.
Structure. 2008 Nov 12;16(11):1689-701. doi: 10.1016/j.str.2008.09.005.
Structure. 2008.
PMID: 19000821
Free PMC article.
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Blue ferrocenium azurin: an organometalloprotein with tunable redox properties.
Hwang HJ, Carey JR, Brower ET, Gengenbach AJ, Abramite JA, Lu Y.
Hwang HJ, et al. Among authors: brower et.
J Am Chem Soc. 2005 Nov 9;127(44):15356-7. doi: 10.1021/ja054983h.
J Am Chem Soc. 2005.
PMID: 16262384
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